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Table 3 Prevalence of IGT/Diabetes and Hypertension in relation to genotype

From: Relationship of APOA5, PPARγ and HL gene variants with serial changes in childhood body mass index and coronary artery disease risk factors in young adulthood

SNP

 

IGT/Diabetes present %(n)

P value

Hypertension present %(n)

P value

APOA5 (-1131T >C)

(Dominant Model)

TT & TC

15.2 (1093)

0.168

9.6 (1132)

0.387

 

CC

22.0 (41)

 

11.9 (42)

 

APOA5 (-1131T >C)

(Recessive Model)

TT

14.9 (753)

0.258

10.4 (778)

0.151

 

TC &CC

16.5(381)

 

8.3 (396)

 

APOA5 (S19W)

(Dominant Model)

SS & SW

15.3 (1044)

0.717

8.9 (1087)

0.246

 

WW

0.0 (2)

 

33.3 (3)

 

APOA5 (S19W)

(Recessive Model)

SS

15.6 (967)

0.203

8.8 (1008)

0.312

 

SW&WW

11.4 (79)

 

11.0 (82)

 

HL (C-514T)

(Dominant Model)

CC & CT

15.6 (1151)

0.233

9.8 (1192)

0.480

 

TT

19.4 (72)

 

10.5 (76)

 

HL (C-514T)

(Recessive Model)

CC

14.3 (732)

0.055

9.5 (761)

0.313

 

CT&TT

17.9 (491)

 

10.5 (507)

 

PPARγ (Pro12Ala)

(Dominant Model)

Pro12Pro & Pro12Ala

15.5 (1104)

0.546

9.6 (1148)

0.476

 

Ala12Ala

16.7 (18)

 

5.6 (18)

 

PPARγ (Pro12Ala)

(Recessive Model)

Pro12Pro

15.2 (884)

0.297

8.7 (921)

0.042

 

Pro12Ala & Ala12Ala

16.8 (238)

 

12.7 (245)