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Table 3 Phospholipids fatty acid composition of PUFA-treated MCF7

From: Effects of n-3 PUFAs on breast cancer cells through their incorporation in plasma membrane

 

C16:0

C16:1

C18:0

C18:1

C18:2

C18:3

C20:3

C20:4

C20:5

C22:5

C22:6

SFA

MUFA

PUFA

n-6 PUFA

n-3 PUFA

Omega-6/Omega-3

AA/EPA

AA/DHA

PE CTR

7.76

4.23

22.01

23.50

3.46

0.69

1.70

24.93

5.28

0.72

5.71

29.77

27.73

42.50

30.09

12.41

2.47

4.75

4.58

s.d.

1.18

1.91

1.92

3.14

0.69

0.14

0.28

3.13

0.69

0.56

1.37

1.86

3.83

3.88

2.66

1.96

0.37

0.50

1.04

PE AA

8.24

1.52*

33.44*

8.05*

1.38*

0.28*

0.49*

42.32*

0.70*

1.03

2.56*

41.68*

9.57*

48.75*

44.19*

4.57*

9.97*

76.64*

17.85*

s.d.

1.62

0.95

1.22

1.04

0.20

0.04

0.25

2.15

0.47

0.39

0.81

1.44

1.57

2.19

1.94

0.86

1.80

30.68

5.10

PE EPA

9.52

2.19*

27.35*

8.58*

1.50*

0.30*

0.53*

7.37*

33.91*

7.68*

1.07*

36.87*

10.77*

52.36*

9.40*

42.96*

0.23*

0.22*

5.42

s.d.

2.55

1.22

2.29

2.80

0.52

0.10

0.26

1.10

4.88

2.26

0.50

1.58

4.00

5.13

1.76

6.77

0.08

0.06

0.45

PE DHA

9.26

1.36*

25.39

6.97*

2.08*

0.42*

1.03

6.62*

9.45*

0.52

36.92*

34.65*

8.33*

57.02*

9.73*

47.30*

0.21*

0.71*

0.19*

s.d.

2.80

1.10

4.61

2.50

1.24

0.25

1.00

1.43

2.19

0.33

7.43

4.38

2.66

6.35

1.95

6.27

0.05

0.13

0.08

PI CTR

10.84

2.51

31.95

18.13

3.43

0.69

5.50

14.10

2.22

1.64

8.99

42.79

20.65

36.56

23.02

13.54

1.80

8.04

1.84

s.d.

5.40

2.32

5.42

6.55

1.29

0.26

1.53

3.89

1.65

1.00

3.07

5.35

7.91

7.50

4.66

3.77

0.47

4.32

1.20

PI AA

8.22

1.04*

35.22*

6.79*

1.45*

0.29*

1.01*

40.65*

0.96*

1.52

2.83*

43.44

7.83*

48.73*

43.12*

5.61*

8.34*

69.09*

23.36*

s.d.

1.78

0.73

2.36

3.69

0.34

0.07

0.13

3.84

0.80

1.41

1.77

2.35

4.03

2.81

3.70

1.65

2.63

49.53

17.92

PI EPA

8.81

1.66

33.04

6.85*

2.18*

0.44*

1.48*

10.41*

24.41*

8.60*

2.13*

41.84

8.51*

49.65*

14.07*

35.57*

0.40*

0.44*

4.76

s.d.

1.58

1.04

1.55

2.31

0.79

0.16

0.61

0.92

4.29

1.69

2.18

1.73

2.04

2.96

1.61

3.59

0.08

0.10

3.02

PI DHA

9.06

1.23*

24.60*

13.54

4.52

0.91

3.11

7.63*

7.71*

0.87*

26.82*

33.66*

14.77*

51.57*

15.26*

36.31*

0.43*

1.16*

0.31*

s.d.

3.81

0.91

5.96

5.74

2.54

0.51

3.09

1.55

3.67

0.76

6.04

6.91

5.63

7.46

5.64

5.29

0.19

0.48

0.17

PS CTR

10.79

3.53

24.95

27.92

4.30

0.86

4.21

11.93

3.18

2.19

6.14

35.75

31.45

32.81

20.43

12.37

1.83

5.17

2.49

s.d.

3.01

2.22

8.41

7.49

1.77

0.35

1.57

5.37

1.91

2.00

3.36

8.35

8.32

8.96

7.21

4.27

0.84

4.46

1.57

PS AA

11.97

1.92

29.81

12.97*

2.24*

0.45*

1.07*

33.50*

1.21*

1.69

3.18*

41.78*

14.89*

43.33*

36.80*

6.53*

6.49*

38.97*

12.22*

s.d.

4.28

2.83

7.69

4.92

1.33

0.27

0.43

11.48

0.63

2.12

1.47

5.84

7.35

9.32

10.79

2.15

3.45

31.62

6.48

PS EPA

16.78*

1.07*

20.16

7.31*

1.27*

0.25*

1.36*

7.62

33.04*

8.11*

3.05

36.93

8.37*

54.70*

10.25*

44.45*

0.22*

0.22*

4.62

s.d.

3.53

0.69

11.14

3.65

0.53

0.11

0.66

3.42

12.94

3.14

3.04

11.06

3.52

14.23

3.84

10.79

0.06

0.06

4.12

PS DHA

9.83

1.78*

24.73

13.57*

3.40

0.68

1.75*

6.67*

5.00

1.55

31.06*

34.56

15.35*

50.10*

11.82*

38.28*

0.32*

1.85*

0.22*

s.d.

3.89

1.47

6.84

3.83

1.70

0.34

1.30

3.26

2.94

0.59

2.17

6.22

3.88

4.33

5.70

4.53

0.18

1.50

0.12

PC CTR

28.42

13.13

6.51

36.22

4.19

0.84

1.52

5.18

1.18

0.59

2.23

34.93

49.35

15.73

10.89

4.83

2.61

5.70

3.91

s.d.

4.83

5.72

1.57

4.15

0.85

0.17

0.66

1.79

0.62

0.92

2.01

3.83

4.82

5.01

2.61

2.95

0.85

3.65

3.51

PC AA

28.28

4.97*

10.89*

16.67*

1.92*

0.38*

0.58*

34.61*

0.19*

0.29

1.21*

39.16*

21.65*

39.19*

37.11*

2.08*

18.12*

222.12*

30.38*

s.d.

2.59

1.87

2.23

0.69

0.05

0.01

0.05

1.68

0.10

0.07

0.33

0.63

1.61

1.91

1.61

0.33

2.44

100.56

8.64

PC EPA

36.02

8.05

5.93

19.61*

2.64*

0.53*

0.56*

3.72

20.12*

1.75

1.07

41.95*

27.66*

35.69*

6.92*

23.48*

0.34*

0.21*

4.37

s.d.

4.52

3.18

0.62

4.19

0.29

0.06

0.34

1.29

8.27

1.39

0.63

0.91

6.34

0.53

1.68

9.30

0.17

0.10

2.54

PC DHA

29.09

3.68*

9.94*

14.94*

3.37*

0.67*

1.42

5.14

10.01*

0.39

21.34*

39.03*

18.62*

42.35*

9.93

32.42*

0.32*

0.51*

0.26*

s.d.

5.46

2.60

1.71

3.86

0.46

0.09

0.39

0.99

1.36

0.20

5.63

4.11

5.19

6.44

1.47

6.01

0.07

0.06

0.08

SM CTR

29.95

3.73

15.64

18.03

3.22

0.64

1.86

13.35

4.32

3.66

5.59

45.60

21.76

32.64

18.43

14.22

1.60

4.45

6.27

s.d.

10.86

3.23

5.22

12.01

2.59

0.52

1.75

7.22

2.64

4.77

6.24

14.67

13.34

11.00

7.83

7.61

1.01

4.12

7.52

SM AA

17.58*

2.89

11.48*

20.36

2.56

0.51

2.16

17.74

4.16

6.86

5.97

29.06*

23.25

47.70*

22.46

15.86

1.50

6.56

3.41

s.d.

3.70

1.81

2.48

14.89

1.24

0.25

1.20

4.82

2.46

2.41

2.77

5.41

15.15

13.59

5.90

5.92

0.48

5.17

1.33

SM EPA

22.22*

13.52*

10.43*

5.06*

1.62*

0.32*

5.71

10.28

7.24

7.54*

16.06

32.65*

18.57

48.78*

17.62

31.16*

0.59*

1.49*

0.74*

s.d.

2.85

2.24

1.59

0.20

0.65

0.13

3.16

3.56

2.52

1.84

8.51

3.98

2.43

5.54

4.86

6.18

0.22

0.52

0.37

SM DHA

27.05

5.19

11.33*

23.02

3.99

0.80

1.30

9.78

2.65*

4.38

10.53

38.38

28.21

33.41

15.06*

18.35

0.94

4.00

1.05*

s.d.

10.74

4.69

2.93

20.63

1.93

0.39

0.89

5.93

0.60

3.81

8.19

12.47

18.30

15.33

6.22

11.75

0.41

2.60

0.47

  1. Values are expressed as percentage of total fatty acids (means bold numbers, SD plain numbers).
  2. CTR n=5, Treated n=6; * P < 0.01