Figure 4

Effect of simvastatin on the expression of transporter genes involved in cholesterol efflux in peritoneal macrophages. A, Effect of simvastatin on the mRNA expression of macrophage transporter genes by real-time PCR. Expression levels of mRNA are indicated as fold differences compared with model mice. B, Effect of simvastatin on the protein expression of macrophage transporter genes by western blots. C, Densitometric quantitation of western blot data (n = 5) by Quantity One software. * P < 0.05 versus model group