Figure 4From: α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytesα-Linolenic acid protects primary rat hepatocytes against ER stress induced by thapsigargin. (A)Western blot image and densitometric analysis of (B) GRP78 and (C) CHOP expression in cells treated with thapsigargin (Thap; 5 μmol/l) in presence of increasing concentrations of α-linolenic acid (ALA) for 16 h. Data represent mean ± S.E.M., n = 5, *P < 0.05 vs. LG, low glucose control (0 μmol/l stearic acid), **P < 0.05 vs. thapsigargin-only cells.Back to article page