Screening of soy protein-derived hypotriglyceridemic di-peptides in vitro and in vivo

Table 2 Effects of dietary soy peptides on growth parameters and activities of hepatic triglyceride metabolism-related enzymes in Otsuka Long-Evans Tokushima fatty rats

	Control	Soy crude peptide-LD3	Hydrophilic peptide
Initial body weight (g)	465 ± 11	467 ± 7	463 ± 9
Final body weight (g)	558 ± 10	554 ± 7	550 ± 8
Food intake (g)	743 ± 3	740 ± 8	738 ± 10
Liver weight (g/100 g b.w.)	3.45 ± 0.05^a	3.14 ± 0.05^b	3.16 ± 0.06^b
Hepatic enzyme activity (nmol/min/mg protein)
FAS	17.0 ± 0.7^a	13.6 ± 0.8^b	13.3 ± 1.3^b
G6PDH	127 ± 7^a	82.7 ± 4.2^b	77.0 ± 5.2^b
Malic enzyme	115 ± 5^a	79.0 ± 3.7^b	86.5 ± 2.1^b
PAP	17.3 ± 1.1^a	14.5 ± 0.5^b	14.8 ± 0.5^b
CPT	5.16 ± 0.31	5.66 ± 0.25	5.42 ± 0.10

FAS, fatty acid synthase; G6PDH, glucose 6-phosphate dehydrogenase; PAP, phosphatidate phosphohydrolase; CPT, carnitine palmitoyltransferase.
Values are expressed as mean ± standard error of 6 rats.
Different superscript letters indicate a significant difference at P < 0.05.

ISSN: 1476-511X