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Table 5 Summary of echocardiographic measurements, myocardial hydroxyproline and triglyceride content and myocyte area

From: The role of dietary fatty acids in predicting myocardial structure in fat-fed rats

 

CON

SAT

SAT+LA

SAT+ALA

p

Echocardiographic measurements

LVWcr/s (cm)

.309/.008

.329/.009

.371/.018**#

.355/.012*

0.013

LVWcr/d (cm)

.203/.005

.201/.003

.230/.010*#

.227/.008*#

0.021

LVWca/s (cm)

.289/.013

.315/.016

.327/.016

.300/.010

0.272

LVWca/d (cm)

.185/.012

.198/.008

.201/.013

.206/.011

0.633

LVIDd (cm)

.824/.027

.799/.009

.798/.018

.809/.030

0.868

LVIDs (cm)

.501/.026

.456/.018

.418/.034

.473/.028

0.234

LV mass:body wt

.0029/.0001

.0028/8.950

e-005

.0028/7.855

e-005

.0028/8.966

e-005

0.695

IVRT (sec)

.026/.001

.029/ < .001

.027/ < .001

.027/ < .001

0.265

FS (%)

39.3/1.54

42.9/2.00

47.8/3.47

41.7/1.91

0.112

Myocardial collagen and triglyceride; myocyte area

Hydroxyproline (ug/mg dry wt)

n = 4-6

.753/.261

.555/.112

.638/.128

.661/.117

0.837

Triglyceride (nMol/gm wet wt)

n = 3-6

9.47/3.67

12.4/1.88

9.11/2.12

9.28/1.21

0.676

Collagen (%)

n = 5-6

.055/.004

.053/.005

.045/.003

.044/.004

0.254

Myocyte cross sectional area (microns2)

n = 5-6

492/30.5

628/23.2**

602/25.1*

610/33.8*

< 0.018

  1. Data listed as mean/SE. LVW, left ventricular wall; LVID, left ventricular internal diameter; IVRT, isovolumic relaxation time; FS, fractional shortening; cr, cranial; ca, caudal; s, systole; d, diastole; CON, Control; SAT, 50% saturated fat; SAT+LA, 40% saturated fat + 10% n-6 PUFA; SAT + ALA, 40% saturated fat + 10% n-3 PUFA.
  2. *p < 0.05 compared to control; **p < 0.01 compared to control; #p < 0.05 compared to SAT.