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Table 2 Clinical Features of the Study Participants in APOC3 Wild-Type Homozygotes (C-482 and T-455) and Carriers of Variant Alleles (C-482T, T-455C or both)

From: Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans

 

Wild Type Homozygotes

(n = 239)

Variant-Allele Carriers

(n = 346)

p valuea

   

Linear regression

Mann-Whitney Test

ALT (U/L)

27 (20-41.5)

29 (21-44)

0.102

0.125

AST (U/L)

19 (16-25)

20 (16-26.7)

0.190

0.366

Triglycerides (mg/dL)

115 (79.9-158.1)

112 (81.6-157)

0.575

0.919

Total Cholesterol (mg/dL)

200 (178.3-229)

200 (178-224.4)

0.726

0.698

HDL Cholesterol (mg/dL)

48 (42.4-56)

48 (41-56.5)

0.617

0.509

LDL Cholesterol (mg/dL)

122 (105.2-149.5)

125 (100.3-145.3)

0.758

0.711

Age (yr)

42 (33-53)

42 (30-51)

0.200

0.261

Body Mass Index (Kg/m 2 )

41 (37-47.3)

41 (36-47.7)

0.813

0.575

Fasting blood glucose (mg/dL)

90 (83-98)

89 (81-100)

0.985

0.697

Fasting blood insulin (μU/mL)

23 (15.4-33)

25 (16.6-36.6)

0.371

0.294

HOMA-IR (U)

5 (3.4-7.7)

5.1 (3.4-8.8)

0.341

0.361

ISI (U)

2.1 (1.4-3.6)

2.1 (1.3-3.3)

0.925

0.609

  1. a P values were calculated using linear regression model including age, BMI and sex. Fasting blood glucose, fasting blood insulin, HOMA-IR and ISI were log-transformed before being entered into the model. Values are medians and interquartile ranges.