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Table 2 Clinical Features of the Study Participants in APOC3 Wild-Type Homozygotes (C-482 and T-455) and Carriers of Variant Alleles (C-482T, T-455C or both)

From: Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans

  Wild Type Homozygotes (n = 239) Variant-Allele Carriers (n = 346) p valuea
    Linear regression Mann-Whitney Test
ALT (U/L) 27 (20-41.5) 29 (21-44) 0.102 0.125
AST (U/L) 19 (16-25) 20 (16-26.7) 0.190 0.366
Triglycerides (mg/dL) 115 (79.9-158.1) 112 (81.6-157) 0.575 0.919
Total Cholesterol (mg/dL) 200 (178.3-229) 200 (178-224.4) 0.726 0.698
HDL Cholesterol (mg/dL) 48 (42.4-56) 48 (41-56.5) 0.617 0.509
LDL Cholesterol (mg/dL) 122 (105.2-149.5) 125 (100.3-145.3) 0.758 0.711
Age (yr) 42 (33-53) 42 (30-51) 0.200 0.261
Body Mass Index (Kg/m 2 ) 41 (37-47.3) 41 (36-47.7) 0.813 0.575
Fasting blood glucose (mg/dL) 90 (83-98) 89 (81-100) 0.985 0.697
Fasting blood insulin (μU/mL) 23 (15.4-33) 25 (16.6-36.6) 0.371 0.294
HOMA-IR (U) 5 (3.4-7.7) 5.1 (3.4-8.8) 0.341 0.361
ISI (U) 2.1 (1.4-3.6) 2.1 (1.3-3.3) 0.925 0.609
  1. a P values were calculated using linear regression model including age, BMI and sex. Fasting blood glucose, fasting blood insulin, HOMA-IR and ISI were log-transformed before being entered into the model. Values are medians and interquartile ranges.