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Table 2 Antioxidant status and oxidative damage in SHRSP rats fed canola oil compared with soybean oil diets.

From: Differential effects of dietary canola and soybean oil intake on oxidative stress in stroke-prone spontaneously hypertensive rats

 

Pre-treatment

Post-treatment

  

Soybean oil

Canola oil

RBC SOD (U/gm Hb)

1608.7 ± 121.8

1454 ± 111.3

1087.2 ± 92.9*, #

RBC GPx (U/gm Hb)

523.0 ± 25.9

512 ± 36.6

415 ± 19.4*, #

RBC Catalase (mmol/min/gm Hb)

155.6 ± 13.4

208.2 ± 35.1

142.4 ± 15.9*

RBC MDA (μM)

28.6 ± 1.6

16.6 ± 3.5#

21.8 ± 3.9

Plasma MDA (μM)

11.8 ± 0.5

17.9 ± 0.5#

14.9 ± 1.3*, #

Plasma 8-isoprostane (pg/ml)

75.2 ± 12.3

103.2 ± 7.6#

83.2 ± 5.6*

  1. Values are means ± SEM; Number of animals at post-treatment was 10. Number of animals in each group at post-treatment for soybean oil and canola oil was 9 and 8, respectively. SOD, superoxide dismutase; GPx, glutathione peroxidase; MDA, malondialdehyde.
  2. *P < 0.05 represents a significant difference between canola and soybean oil groups;
  3. #P < 0.05 represents a significant difference between pre-treatment vs post-treatment.
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Lipids in Health and Disease

ISSN: 1476-511X