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Figure 3 | Lipids in Health and Disease

Figure 3

From: Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells

Figure 3

Anthocyanin suppresses ACC activity, decrease Malonyl CoA levels and prevents FAS expression in HepG2 cells. (A) Western blot analysis of the phosphorylated form of ACC or total ACC in cell lysates from HepG2 cells treated for 1 h with Cy-3-g or AICAR. (B) ACC activity in cellular extracts was measured and expressed as means ± SE. (C-D) HepG2 cells were left alone or treated with various concentrations of Cy-3-g for 6 h. Then cells were collected and lysed for measuring (C) malonyl CoA levels and (D) CPT1 mRNA expression as indicated. Results are expressed as means ± SE. *P < 0.05; **P < 0.01 compared to control.

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