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Figure 7 | Lipids in Health and Disease

Figure 7

From: Cyanidin-3-O-β-glucoside regulates fatty acid metabolism via an AMP-activated protein kinase-dependent signaling pathway in human HepG2 cells

Figure 7

AMPK depletion abolishes the effects of anthocyanin on hepatic fatty acid metabolism. HepG2 cells were infected with a control null adenovirus (Ad-Null) or dominant-negative AMPK (Ad-DN AMPK) either with anthocyanin (Cy-3-g, 100 μM) or without anthocyanin (Control). (A) malonyl CoA levels, (B) CPT-1 mRNA expression, (C) fatty acid oxidation, and (D) TG levels were determined as indicated, respectively. Results acquired from three independent experiments are expressed as means ± SE. *P < 0.05 compared to Ad-Null control.

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Lipids in Health and Disease

ISSN: 1476-511X