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Table 4 Selection of inflammation and immune response related genes regulated in dyslipidemic subjects after supplementation with fish oil for twelve weeks

From: Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: results from a randomized controlled trial

Gene name

Gene symbol

Entrez_ID

Ratio t12: t0

Pro-inflammatory genes

Nitric oxide synthase, inducible

NOS2

4843

-4.77

C-C chemokine receptor type 3

CCR3

1232

-4.49

Tumour necrosis factor receptor superfamily member 18 Precursor

TNFRSF18

8784

-2.07

Interleukin-31 receptor A Precursor

IL31RA

133396

-4.74

72 kDa type IV collagenase Precursor

MMP2

4313

-6.16

Interleukin-8 Precursor

IL8

3576

-5.67

Tumour necrosis factor receptor superfamily member 5 Precursor

CD40

958

-4.72

Interleukin-2 receptor subunit beta Precursor

IL2RB

3560

-3.22

Interleukin-3 receptor subunit alpha Precursor

IL3RA

3563

-2.22

Stromelysin-1 Precursor

MMP3

4314

-2.17

C-C motif chemokine 5 Precursor

CCL5

6352

2.24

CD97 antigen Precursor

CD97

976

2.26

Prostaglandin D2 receptor

PTGDR

5729

4.47

Integrin alpha-L Precursor

ITGAL

3683

5.07

Arachidonate 5-lipoxygenase-activating protein (FLAP)

ALOX5AP

241

6.97

Anti-inflammatory genes

C-X-C motif chemokine 11 Precursor

CXCL11

6373

-2.98

NF-kappa-B-repressing factor

NKRF

55922

-82.11

NF-kappa-B inhibitor-like protein 2

NFKBIL2

4796

-3.30

Cytokine receptor-like factor 1 Precursor

CRLF1

9244

-3.07

Lipopolysaccharide-induced tumour necrosis factor-alpha factor

LITAF

9516

3.06

Interferon regulatory factor 1

IRF1

3659

3.16

Interferon-alpha/beta receptor alpha chain Precursor

IFNAR1

3454

5.13

Suppressor of cytokine signalling 6

SOCS6

9306

6.01

Immune response related genes

Suppressor of cytokine signalling 2

SOCS2

8835

-6.05

Disintegrin and metalloproteinase domain-containing protein 10 Precursor

ADAM10

102

-5.23

A disintegrin and metalloproteinase with thrombospondin motifs 10 Precursor

ADAMTS10

81794

-3.14

Nitric oxide synthase, endothelial

NOS3

4846

-2.55

SL cytokine Precursor

FLT3LG

2323

-2.46

Prostaglandin E2 receptor EP3 subtype

PTGER3

5733

-2.21

CD99 antigen-like protein 2 Precursor

CD99L2

83692

2.18

Cytokine receptor common gamma chain Precursor

IL2RG

3561

2.85

Monocyte differentiation antigen CD14 Precursor

CD14

929

2.88

Chemokine-like factor (C32)

CKLF

51192

11.73

T-cell surface glycoprotein CD3 delta chain Precursor

CD3D

915

7.65

Tumour necrosis factor receptor superfamily member 1B Precursor

TNFRSF1B

7133

2.51

B-lymphocyte antigen CD20

MS4A1

931

2.12

Interleukin-31 receptor A Precursor

IL31RA

133396

5.72

Intercellular adhesion molecule 3 Precursor

ICAM3

3385

5.85

CD320 antigen Precursor

CD320

51293

8.17

CD2 antigen cytoplasmic tail-binding protein 2

CD2BP2

10421

8.77

T-cell antigen CD7 Precursor

CD7

924

2.30

C-C chemokine receptor-like 2 (Putative MCP-1 chemokine receptor)

CCRL2

9034

17.55