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Table 2 Body weight change, food intake, and feeding efficiency ratio (FER) of rats fed HC diets and treated with separate and combined doses of β-conglycinin, fenofibrate and rosuvastatin.

From: β-conglycinin combined with fenofibrate or rosuvastatin have exerted distinct hypocholesterolemic effects in rats

  Dietary groups1
  HC HC+7S HC+FF HC+RO HC+7S+FF HC+7S+RO
Initial weight (g/rat) 196.55 ± 4.63 195.26 ± 3.64 193.26 ± 3.64 193.33 ± 2.27 193.18 ± 3.62 194.22 ± 3.14
Final weight (g/rat) 295.01 ± 5.43 300.64 ± 7.71 281.14 ± 4.25 306.11 ± 3.79 306.64 ± 7.71 284.33 ± 8.01
Weight gain (g/rat/day) 3.51 ± 0.32 3.76 ± 0.29 3.14 ± 0.29 4.02 ± 0.16 4.05 ± 0.17 3.22 ± 0.28
Food intake (g/rat/day) 16.74 ± 0.33 16.25 ± 0.22 16.25 ± 0.22 18.20 ± 0.17** 15.61 ± 0.30 17.68 ± 0.25
Fecal excretion (g/rat/day) 3.59 ± 0.12 2.94 ± 0.09* 2.94 ± 0.09* 2.05 ± 0.12** 2.83 ± 0.09* 1.77 ± 0.13**
Feeding efficiency (%) 21.01 ± 1.44 23.05 ± 1.93 23.21 ± 1.93 21.35 ± 0.85 20.90 ± 1.51 18.25 ± 1.34
  1. 1Values are means ± SEM for nine rats. *p < 0.05 and **p < 0.001 by the Bonferroni t-test for multiple comparisons versus control group (HC). HC = hypercholesterolemic diet; HC+7S = HC diet + β-conglycinin 300 mg/kg/day; HC+FF = HC diet + fenofibrate 30 mg/kg/day; HC+RO = HC diet + rosuvastatin 10 mg/Kg/day; HC+7S+FF = HC diet + β-conglycinin + fenofibrate, 300 and 30 mg/kg/day respectively, and HC+7S+RO = HC diet + β-conglycinin + rosuvastatin, 300 and 10 mg/kg/day respectively.
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Lipids in Health and Disease

ISSN: 1476-511X