Table 1 Charactaristics and lipoprotein profiles of hemodialysis patients and healthy controls
| Â | Hemodialysis patients | Healthy controls | P value |
|---|---|---|---|
|  | (n = 25) | (n = 25) |  |
Age (years) | 63 ± 13 | 63 ± 3 | NS |
Sex (male/female) | 10/15 | 15/10 | NS |
Duration of hemodialysis (years) | 1.9 ± 1.0 |  |  |
BMI (kg/m2) | 21 ± 3 | 22 ± 2 | NS |
Total cholesterol (mmol/L) | 4.28 ± 1.02 | 5.07 ± 0.30 | <0.005 |
Triglyceride (mmol/L) | 1.00 ± 0.35 | 0.86 ± 0.31 | NS |
LDL cholesterol (mmol/L) | 2.22 ± 0.72 | 3.00 ± 0.33 | <0.0001 |
HDL cholesterol (mmol/L) | 1.29 ± 0.43 | 1.68 ± 0.32 | <0.001 |
Creatinine(mmol/L) | 0.810 ± 0.204 | 0.061 ± 0.010 | <0.0001 |
Estimated GFR (mL/min/1.73 m2) | 4.1 ± 1.9 | 69.6 ± 15.3 | <0.0001 |
Anion-exchange chromatgraphic method | Â | Â | Â |
Nonelectronegative-HDL cholesterol (mmol/L) | 0.54 ± 0.13 | 0.82 ± 0.11 | <0.0001 |
Electronegative-HDL cholesterol (mmol/L) | 0.86 ± 0.36 | 0.75 ± 0.26 | NS |
Nonelectronegative-LDL cholesterol (mmol/L) | 2.29 ± 0.78 | 2.87 ± 0.30 | <0.05 |
Electronegative-LDL cholesterol (mmol/L) | 0.32 ± 0.13 | 0.34 ± 0.09 | NS |
IDL cholesterol (mmol/L) | 0.099 ± 0.040 | 0.074 ± 0.035 | <0.05 |
VLDL cholesterol (mmol/L) | 0.23 ± 0.12 | 0.20 ± 0.10 | NS |
Chylomicron cholesterol (mmol/L) | 0.075 ± 0.037 | 0.077 ± 0.063 | NS |
Electronegative-LDL-s / total LDL (%) | 12.5 ± 3.4 | 10.4 ± 2.2 | <0.05 |