A potential synbiotic product improves the lipid profile of diabetic rats

Table 3 Concentrations of liver enzymes in non-diabetic and diabetic groups during the trial period

Group	Group I	Group II	Group III	Group IV
Parameters/
Time
AST
T0	164.18^B.a ± 7.48	168.78^B.a ± 9.55	163.45^A.a ± 7.72	159.00^B.a ± 10.22
T1	156.50^B.a ± 9.33	159.75^B.a ± 15.15	180.10^A.a ± 11.90	175.7^AB.a ± 12.64
T2	208.09^A.a ± 8.24	283.90^A.a ± 35.68	219.36^A.a ± 14.85	254.20^A.a ± 29.05
T3	150.45^B.a ± 9.20	166.56^B.a ± 29.97	171.64^A.a ± 25.03	164.25^B.a ± 16.97
ALT
T0	74.60^AB.a ± 3.49	78.25^B.a ± 2.59	73.18^B.a ± 2.98	67.50^C.a ± 1.57
T1	63.10^C.a ± 2.25	67.5^B.a ± 1.88	61.46^B.a ± 1.87	59.25^C.a ± 2.43
T2	68.90^B.b ± 1.75	126.80^A.a ± 18.05	151.63^A.a ± 10.80	136.80^B.a ± 12.38
T3	83.80^A.b ± 2.61	150.00^A.a ± 9.25	163.00^A.a ± 12.85	163.83^A.a ± 5.50

Values are expressed in U/L (n=10, mean ± standard error). Comparisons between groups: mean values with the same lowercase letter on the same line do not differ significantly at p ≤ 0.05, and times: equal means with capital letters in the same column do not differ significantly p ≤ 0.05. Group I = non-diabetic animals that received only chow diet (negative control), Group II = diabetic animals that received only chow diet (positive control), Group III = diabetic animals that received chow diet + 1 mL/kg bw/day of soybean and yacon unfermented product, Group IV = diabetic animals that received chow diet + 1 mL/kg bw/day of soybean and yacon unfermented product. T0 = initial blood collection, T1 = blood collection after a week to confirm the induction of diabetes mellitus, T2 = blood collection after four weeks to detected any reversal of the diabetic state, T3 = blood collection when sacrificed at end of experiment (seven weeks).

ISSN: 1476-511X