A potential synbiotic product improves the lipid profile of diabetic rats

Table 4 Lipid profile in non-diabetic and diabetic groups during the trial period

Groups	Group I	Group II	Group III	Group IV
Parameters/
Time
Triglycerides
T0	135.10^B.a ± 12.62	173.73^B.a ± 11.46	156.64^B.a ± 12.51	175.36^C.a ± 13.37
T2	188.82^A.b ± 12.90	425.33^AB.a ± 84.89	396.18^A.a ± 49.70	348.50^AB.a ± 31.14
T3	149.55^AB.c ± 9.95	628.67^A.a ± 32.05	503.25^A.b ± 25.79	419.00^A.b ± 35.39
Total cholesterol
T0	101.37^A.a ± 4.66	111.73 ^A.a ± 3.33	99.64^A.a ± 2.81	98.9^A.a ± 2.71
T2	80.78^B.b ± 3.30	100.79^A.a ± 4.97	102.46^A.a ± 3.73	100.25^A.a ± 4.07
T3	69.82^B.b ± 5.52	96.78^A.a ± 5.61	97.64^A.a ± 2.96	90.33^A.a ± 4.84
HDL-C
T0	45.27^A.a ± 1.92	55.82^A.a ± 3.64	50.09^A.a ± 1.66	52.82^A.a ± 3.25
T2	43.82^A.a ± 2.59	52.40 ^A.a ± 2.20	48.64^A.a ± 1.50	48.70^A.a ± 2.25
T3	34.37^B.c ± 2.13	52.44^A.b ± 1.70	52.27^A.b ± 1.61	65.00^A.a ± 6.36
nHDL-C
T0	39.56^B.a ± 2.35	48.57^A.a ± 2.81	48.63^A.a ± 2.15	45.50^A.a ± 3.01
T2	35.46^B.a ± 4.19	48.13^A.a ± 3.93	45.37^A.a ± 2.66	39.40^A.a ± 2.16
T3	56.09^A.a ± 3.60	55.91^A.a ± 3.88	49.55^A.a ± 2.92	46.09 ^A.a ± 3.19

Values are expressed in mg/dL (n=10, mean ± standard error). Means values for groups with lowercase letters on the same line do not differ significantly at p ≤ 0.05; comparing times, means with same capital letters in the same column do not differ significantly p ≤ 0.05. Group I = non-diabetic animals that received only chow diet (negative control), Group II = diabetic animals that received only chow diet (positive control), Group III = diabetic animals that received chow diet + 1 mL/kg bw/day of soybean and yacon unfermented product, Group IV = diabetic animals that received chow diet + 1 mL/kg bw/day of soybean and yacon unfermented product. T0 = initial blood collection, T2 = blood collection after four weeks to detect any reversal of the diabetic condition, T3 = blood collection when sacrificed at end of experiment (seven weeks).

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