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Table 2 Identification results of proteins differentially expressed in basal and after ω-3 PUFAs supplementation

From: Beneficial effects of omega-3 fatty acids in the proteome of high-density lipoprotein proteome

Spot Protein name ANOVA (p < 0.05) Fold change Protein expression level after ω-3 supplementation UniProt ID Entry name Mascot score Sequence coverage (%) Number of Peptidic masses identified Number of MS/MS identified MW (KDa) pI
837 Apolipoprotein A-I 0.044 1.18 Up-regulated P02647 APOA1 87 42 10 1 30.8 5.56
997 Clusterin 0.029 1.3 Up-regulated P10909 CLUS 735 47 30 8 53 5.89
610 Fibrinogen β 0.048 1.1 Up-regulated P02675 FIBB 233 49 29 4 56.6 8.54
612 Fibrinogen β 0.045 1.1 Up-regulated P02675 FIBB 140 45 20 1 56.6 8.54
721* Clusterin 0.02 1.4 Up-regulated P10909 CLUS 519 23   11 53 5.89
Apolipoprotein A-I 0.02 1.4 Up-regulated P02647 APOA1 478 39   13 30.8 5.56
Haptoglobin-related protein 0.02 1.4 Up-regulated P00739 HPTR 477 26   12 39.5 6.63
732 Haptoglobin-related protein 0.015 1.37 Up-regulated P00739 HPTR 79 31 14 4 39.5 6.63
965 Serum paraoxonase 0.003 1.6 Up-regulated P27169 PON1 142 15 9 4 39.8 5.08
970 Serum paraoxonase 0.003 1.97 Up-regulated P27169 PON1 411 56 24 8 39.8 5.08
973 Serum paraoxonase 0.003 1.86 Up-regulated P27169 PON1 235 31 14 4 39.8 5.08
825* Ig kappa chain C region 0.036 1.27 Up-regulated P01834 IGKC 872 86   8 11.6 5.87
Apolipoprotein A-I 0.036 1.27 Up-regulated P02647 APOA1 397 52   15 30.8 5.56
578* α-1-antitrypsin 0.001 0.74 Donw-regulated P01009 A1AT 364 51   18 46.7 5.59
986* Complement C1r subcomponent 0.018 0.85 Donw-regulated P00736 C1R 1601 65   45 80.1 6.21
987* Serum Albumin 0.032 0.85 Donw-regulated P02768 ALBU 1114 75   46 69.3 6.3
Ig mu Chain C region 0.032 0.85 Donw-regulated P01871 IGHM 987 57   25 49.3 6.8
Complement C1r subcomponent 0.032 0.85 Donw-regulated P00736 C1R 784 46   28 80.1 6.2
324 Complement Factor H 0.017 0.72 Donw-regulated P08603 CFAH 72 16 19 1 14.4 6.21
980* Fibronectin 0.01 0.66 Donw-regulated P02751 FN1 1434 26   40 262.5 5.71
981* Fibronectin 0.002 0.67 Donw-regulated P02751 FN1 1437 30   48 262.5 5.71
  1. Spots label with a * denotes identification by Orbitrap. Positive fold changes denote proteins up-regulated while negative fold changes denote decrease protein expression after the supplementation. MW denotes Molecular Weight. pI denotes Isoelectric point.