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Table 1 Plasma lipid profile of SFA mice randomised to SFA diet + drugs for 2 weeks

From: Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents

   

SFA 12wk

 

 
 

LF 12wk

SFA 12wk

LF + At 2wk

SFA + At 2wk

LF + Pr 2wk

SFA + Pr 2wk

LF + Ib 2wk

SFA + Ib 2wk

Cholesterol (mM)

1.83 ± 0.20

1.54 ± 0.20

1.68 ± 0.11

1.69 ± 0.05

1.64 ± 0.13

1.91 ± 0.13

1.93 ± 0.12

1.59 ± 0.13

Triglycerides (mM)

0.74 ± 0.08

0.34 ± 0.04a

0.39 ± 0.03a

0.34 ± 0.02a

0.36 ± 0.01a

0.40 ± 0.04a

0.42 ± 0.03a

0.31 ± 0.02a

NEFA (mEq/L)

0.85 ± 0.08

0.68 ± 0.04

0.93 ± 0.05

0.82 ± 0.04

1.02 ± 0.05b

0.90 ± 0.08

1.05 ± 0.10b

0.79 ± 0.05

  1. The table shows the effects of various feeding regimens on plasma lipids. Plasma total cholesterol, triglycerides and non-esterified fatty acids (NEFA) were measured at the end of the feeding regimen. Data represented as mean ± standard error of mean. Means were compared with non-parametric independent t test, where P < 0.05 considered statistically significant.
  2. a: statistically significant in comparison to LF;
  3. b: statistically significant in comparison to SFA.
  4. Abbreviations: LF, low-fat; SFA, saturated fatty acids; At, atorvastatin; Pr, pravastatin; Ib, ibuprofen; wk, weeks.