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Table 1 Plasma lipid profile of SFA mice randomised to SFA diet + drugs for 2 weeks

From: Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents

    SFA 12wk
  ↓  
  LF 12wk SFA 12wk LF + At 2wk SFA + At 2wk LF + Pr 2wk SFA + Pr 2wk LF + Ib 2wk SFA + Ib 2wk
Cholesterol (mM) 1.83 ± 0.20 1.54 ± 0.20 1.68 ± 0.11 1.69 ± 0.05 1.64 ± 0.13 1.91 ± 0.13 1.93 ± 0.12 1.59 ± 0.13
Triglycerides (mM) 0.74 ± 0.08 0.34 ± 0.04a 0.39 ± 0.03a 0.34 ± 0.02a 0.36 ± 0.01a 0.40 ± 0.04a 0.42 ± 0.03a 0.31 ± 0.02a
NEFA (mEq/L) 0.85 ± 0.08 0.68 ± 0.04 0.93 ± 0.05 0.82 ± 0.04 1.02 ± 0.05b 0.90 ± 0.08 1.05 ± 0.10b 0.79 ± 0.05
  1. The table shows the effects of various feeding regimens on plasma lipids. Plasma total cholesterol, triglycerides and non-esterified fatty acids (NEFA) were measured at the end of the feeding regimen. Data represented as mean ± standard error of mean. Means were compared with non-parametric independent t test, where P < 0.05 considered statistically significant.
  2. a: statistically significant in comparison to LF;
  3. b: statistically significant in comparison to SFA.
  4. Abbreviations: LF, low-fat; SFA, saturated fatty acids; At, atorvastatin; Pr, pravastatin; Ib, ibuprofen; wk, weeks.
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