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Table 2 Plasma lipid profile of SFA mice switched to diets + drug for 8 weeks

From: Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents

   

SFA 12wk

 

 
 

LF 20wk

SFA 20wk

LF + At 8wk

SFA + At 8wk

LF + Pr 8wk

SFA + Pr 8wk

LF + Ib 8wk

SFA + Ib 8wk

Cholesterol (mM)

1.64 ± 0.14

1.43 ± 0.08

1.17 ± 0.11a

1.55 ± 0.14

1.52 ± 0.17

1.37 ± 0.09

1.81 ± 0.26

1.19 ± 0.11a

Triglycerides (mM)

0.80 ± 0.12

0.55 ± 0.14

0.40 ± 0.04a

0.63 ± 0.09

0.89 ± 0.09b

1.00 ± 0.17b

0.57 ± 0.07

0.80 ± 0.14

NEFA (mEq/L)

0.70 ± 0.04

0.61 ± 0.07

0.50 ± 0.07a

0.62 ± 0.05

0.62 ± 0.06

0.51 ± 0.04a

0.52 ± 0.04a

0.52 ± 0.06a

  1. The table shows the effects of various feeding regimens on plasma lipids. Plasma total cholesterol, triglycerides and non-esterified fatty acids (NEFA) were measured at the end of the feeding regimen. Data represented as mean ± standard error of mean. Means were compared with non-parametric independent t test, where P < 0.05 considered statistically significant.
  2. a: statistically significant in comparison to LF.
  3. b: statistically significant in comparison to SFA.
  4. Abbreviations: LF, low-fat; SFA, saturated fatty acids; At, atorvastatin; Pr, pravastatin; Ib, ibuprofen; wk, weeks.