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Table 2 Plasma lipid profile of SFA mice switched to diets + drug for 8 weeks

From: Restoration of dietary-fat induced blood–brain barrier dysfunction by anti-inflammatory lipid-modulating agents

    SFA 12wk
  ↓  
  LF 20wk SFA 20wk LF + At 8wk SFA + At 8wk LF + Pr 8wk SFA + Pr 8wk LF + Ib 8wk SFA + Ib 8wk
Cholesterol (mM) 1.64 ± 0.14 1.43 ± 0.08 1.17 ± 0.11a 1.55 ± 0.14 1.52 ± 0.17 1.37 ± 0.09 1.81 ± 0.26 1.19 ± 0.11a
Triglycerides (mM) 0.80 ± 0.12 0.55 ± 0.14 0.40 ± 0.04a 0.63 ± 0.09 0.89 ± 0.09b 1.00 ± 0.17b 0.57 ± 0.07 0.80 ± 0.14
NEFA (mEq/L) 0.70 ± 0.04 0.61 ± 0.07 0.50 ± 0.07a 0.62 ± 0.05 0.62 ± 0.06 0.51 ± 0.04a 0.52 ± 0.04a 0.52 ± 0.06a
  1. The table shows the effects of various feeding regimens on plasma lipids. Plasma total cholesterol, triglycerides and non-esterified fatty acids (NEFA) were measured at the end of the feeding regimen. Data represented as mean ± standard error of mean. Means were compared with non-parametric independent t test, where P < 0.05 considered statistically significant.
  2. a: statistically significant in comparison to LF.
  3. b: statistically significant in comparison to SFA.
  4. Abbreviations: LF, low-fat; SFA, saturated fatty acids; At, atorvastatin; Pr, pravastatin; Ib, ibuprofen; wk, weeks.
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