Figure 5From: Phenolic-glycolipid-1 and lipoarabinomannan preferentially modulate TCR- and CD28-triggered proximal biochemical events, leading to T-cell unresponsiveness in mycobacterial diseasesMan-LAM and PGL-1 modulate DNA binding affinity of NFAT to the promoter of IL-2 cytokine. Untreated or antigen pretreated Jurkat T-cells were stimulated with PMA/ionomycin and electrophoretic mobility shift assays were performed. Representative blot of experiments were repeated at least three times.Back to article page