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Figure 5 | Lipids in Health and Disease

Figure 5

From: Phenolic-glycolipid-1 and lipoarabinomannan preferentially modulate TCR- and CD28-triggered proximal biochemical events, leading to T-cell unresponsiveness in mycobacterial diseases

Figure 5

Man-LAM and PGL-1 modulate DNA binding affinity of NFAT to the promoter of IL-2 cytokine. Untreated or antigen pretreated Jurkat T-cells were stimulated with PMA/ionomycin and electrophoretic mobility shift assays were performed. Representative blot of experiments were repeated at least three times.

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