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Figure 9 | Lipids in Health and Disease

Figure 9

From: Phenolic-glycolipid-1 and lipoarabinomannan preferentially modulate TCR- and CD28-triggered proximal biochemical events, leading to T-cell unresponsiveness in mycobacterial diseases

Figure 9

Man-LAM and PGL-1 inhibit TCR- and TCR/CD28-induced T-cell proliferation. Bar diagram showing mean ± SEM of tritiated thymidine (3 H) uptake by PBMCs of healthy individuals (N = 5) after stimulation with α-CD3 or α-CD3 + α-CD28 in presence or absence of Man-LAM and PGL-1 at the end of 72 hrs. Experiments were performed in triplicates.

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