Effect of flaxseed supplementation and exercise training on lipid profile, oxidative stress and inflammation in rats with myocardial ischemia

Table 3 Levels of the inflammatory markers IL-1β, PTX 3 and TNF-α in plasma of control and experimental groups of rats

Inflammatory markers	Groups	Median	Interquartile Range	Mean
Interleukin 1-beta (pg/ml)	(4) control	59.5	57.0-60.3	60.0
	(2) Cardiac ischemia	128.0	125.5-130.8	127.8 ^a***
	(3) Flaxseed supplemented	34.7	33.0-40.0	35.1 ^b*^{, d}*
	(4) Flaxseed with exercise	61.5	47.3-68.0	58.1 ^E*^{, F}*
Pentraxin 3 (ng/ml)	(1) Control	0.16	0.13-0.18	0.15
	(2) Cardiac ischemia	0.32	0.25-0.35	0.3^a***
	(3) Flaxseed supplemented	0.15	0.12-0.18	0.18
	(4) Flaxseed with exercise	0.38	0.24-0.41	0.35 ^c^{, F}*
TNF-alpha (pg/ml)	(1) Control	26.6	20.7-30.2	25.9
	(2) Cardiac ischemia	30.7	29.3-31.0	30.3^a*
	(3) Flaxseed supplemented	22.4	21.2-24.9	23.5 ^d***
	(4) Flaxseed with exercise	25.0	23.7-26.5	24.9 ^E***

a: Significant difference between control and myocardial ischemia. b: Significant difference between control and flaxseed supplemented rats. c: Significant difference between control and flaxseed with exercise group. d: Significant difference between groups 2,3. E: Significant difference between groups 2,4 F: Significant difference between groups 3,4.
*: P<0.05; **: P<0.001; ***: P<0.0001.

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