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Table 5 IC50 activities of tyrosol and its acyl chain derivatives against L. major and L. infantum parasite species evaluated by the MTT assay

From: Synthesis of lipophilic tyrosyl esters derivatives and assessment of their antimicrobial and antileishmania activities

Compounds

Ty

TyC2

TyC3

TyC8

TyC10

TyC12

TyC16

TyC18

TyC18:1

IC50 (μg/ml)

L. major

ND

ND

ND

38.09

19.21

60.34

ND

ND

ND

IC50 (μg/ml)

L. infantum

ND

ND

ND

62.8

38.73

157.6

ND

ND

ND

  1. * ND: Without effect up to 400 μg/ml