|
Baseline
|
E2
|
E2+P
|
P
|
---|
Total-c (mg/dL)
|
216 ± 31a
|
207 ± 30b
|
203 ± 32b
|
< 0.01
|
HDL-c (mg/dL)
|
63 ± 16
|
61 ± 15
|
61 ± 15
|
0.06
|
LDL-c (mg/dL)
|
129 ± 29a
|
123 ± 29a,b
|
119 ± 28b
|
< 0.01
|
Triglycerides (mg/dL)
|
120 ± 53
|
115 ± 51
|
111 ± 53
|
0.2
|
Fast glucose (mg/dL)
|
91 ± 11
|
91 ± 8
|
92 ± 11
|
0.2
|
2h glucose (mg/dL)
|
103 ± 27
|
108 ± 36
|
105 ± 36
|
0.2
|
Insulin (μU/mL)
|
6.9 (3.9-9.7)
|
6.2 (2.8 -8.8)
|
6.9 (3.8 -9.1)
|
0.2
|
hsCRP (mg/L)
|
1.51 (0.38-2.9)
|
1.64 (0.4-3)
|
1.19 (0.3-2.1)
|
0.1
|
- Values expressed as median and interquartile range or mean ± SD. P = two-way analysis of variance with repeated measures (non parametric variables were log-converted for statistical analysis and reconverted for presentation in table format).
- Different superscript letters indicate statistical difference with Bonferroni multiple-comparison correction test (α < 5%).
- Baseline: before hormone therapy; E2: estradiol only; E2+P estradiol + micronized progesterone.
- HDL-c high-density lipoprotein cholesterol, hsCRP high-sensitivity C-reactive protein test, LDL-c low-density lipoprotein cholesterol, Total-c total lipoprotein cholesterol; 2h glucose: glucose levels 2 hours after 75g oral glucose load.