| Baseline | E2 | E2+P |
P
|
---|
Total-c (mg/dL) | 216 ± 31a | 207 ± 30b | 203 ± 32b | < 0.01 |
HDL-c (mg/dL) | 63 ± 16 | 61 ± 15 | 61 ± 15 | 0.06 |
LDL-c (mg/dL) | 129 ± 29a | 123 ± 29a,b | 119 ± 28b | < 0.01 |
Triglycerides (mg/dL) | 120 ± 53 | 115 ± 51 | 111 ± 53 | 0.2 |
Fast glucose (mg/dL) | 91 ± 11 | 91 ± 8 | 92 ± 11 | 0.2 |
2h glucose (mg/dL) | 103 ± 27 | 108 ± 36 | 105 ± 36 | 0.2 |
Insulin (μU/mL) | 6.9 (3.9-9.7) | 6.2 (2.8 -8.8) | 6.9 (3.8 -9.1) | 0.2 |
hsCRP (mg/L) | 1.51 (0.38-2.9) | 1.64 (0.4-3) | 1.19 (0.3-2.1) | 0.1 |
- Values expressed as median and interquartile range or mean ± SD. P = two-way analysis of variance with repeated measures (non parametric variables were log-converted for statistical analysis and reconverted for presentation in table format).
- Different superscript letters indicate statistical difference with Bonferroni multiple-comparison correction test (α < 5%).
- Baseline: before hormone therapy; E2: estradiol only; E2+P estradiol + micronized progesterone.
- HDL-c high-density lipoprotein cholesterol, hsCRP high-sensitivity C-reactive protein test, LDL-c low-density lipoprotein cholesterol, Total-c total lipoprotein cholesterol; 2h glucose: glucose levels 2 hours after 75g oral glucose load.