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Table 3 Anthropometric and metabolic variables and markers of endothelial function (n = 86)

From: Effects of micronized progesterone added to non-oral estradiol on lipids and cardiovascular risk factors in early postmenopause: a clinical trial

 

Baseline

E2

E2+P

P

Total-c (mg/dL)

216 ± 31a

207 ± 30b

203 ± 32b

< 0.01

HDL-c (mg/dL)

63 ± 16

61 ± 15

61 ± 15

0.06

LDL-c (mg/dL)

129 ± 29a

123 ± 29a,b

119 ± 28b

< 0.01

Triglycerides (mg/dL)

120 ± 53

115 ± 51

111 ± 53

0.2

Fast glucose (mg/dL)

91 ± 11

91 ± 8

92 ± 11

0.2

2h glucose (mg/dL)

103 ± 27

108 ± 36

105 ± 36

0.2

Insulin (μU/mL)

6.9 (3.9-9.7)

6.2 (2.8 -8.8)

6.9 (3.8 -9.1)

0.2

hsCRP (mg/L)

1.51 (0.38-2.9)

1.64 (0.4-3)

1.19 (0.3-2.1)

0.1

  1. Values expressed as median and interquartile range or mean ± SD. P = two-way analysis of variance with repeated measures (non parametric variables were log-converted for statistical analysis and reconverted for presentation in table format).
  2. Different superscript letters indicate statistical difference with Bonferroni multiple-comparison correction test (α < 5%).
  3. Baseline: before hormone therapy; E2: estradiol only; E2+P estradiol + micronized progesterone.
  4. HDL-c high-density lipoprotein cholesterol, hsCRP high-sensitivity C-reactive protein test, LDL-c low-density lipoprotein cholesterol, Total-c total lipoprotein cholesterol; 2h glucose: glucose levels 2 hours after 75g oral glucose load.