Figure 4

Case study on the effect of several levels of physical activity on LPP1 expression in deep human skeletal muscle. A healthy male subject (25 yrs.) was the tissue donor for all of the repeated measures treatments. The standing/ambulatory control day was normal to low-intensity puttering for 12 hours before the muscle biopsy. During the exercise day, the subject performed aerobic exercise (cycle ergometry and treadmill walking) in addition to normal spontaneous standing/ambulatory activity. For chronic inactivity, the subject sat in a wheelchair for 15 days and exercised one leg daily (but without adding back the natural standing and other low-intensity physical activity), while the other leg never received exercise. After 16 days of sitting, the subject returned to daily standing/ambulatory activity for 12 hours immediately preceding a final biopsy. Diet was controlled the day of and the day before all muscle biopsies which were all taken at the same time of day. Error bars are shown to indicate the variability (SD) between repeated biopsies on the same day.