GENE | Access # | Expression | Frequency | P-value | Function |
---|---|---|---|---|---|
GENE SUPPRESSED BY PHYSICAL INACTIVITY | |||||
LPP1 | AB000888.1 | Strong detection | 8/8 | 0.004 | Dephosphorylates LPA, S1P, PA, ceramide-1-P |
GENES NOT AFFECTED BY PHYSICAL INACTIVITY | |||||
LPP2 | AF047760.1 | Not detected | 0/8 | 0.47 | Dephosphorylates LPA, S1P, PA, ceramide-1-P |
LPP3 | NM_003713 | Strong detection | 8/8 | 0.0007 | Dephosphorylates LPA, S1P, PA, ceramide-1-P |
8/8 | 0.0002 | ||||
LPAP | AB031478.1 | Moderate detection | 2/8 | 0.068 | Dephosphorylates LPA |
SGPP1 | NM_030791 | Moderate detection | 7/8 | 0.024 | Dephosphorylates S1P |
SGPL1 | NM_003901.1 | Not detected | 0/8 | 0.90 | Irreversible sphingosine 1-phosphate degradation |
SPHK1 | NM_021972.1 | Not detected | 0/8 | 0.19 | Phosphorylates sphingosine |
AGPAT1 | U56417 | Strong detection | 8/8 | 0.0029 | ER enzyme converting LPA to PA |
8/8 | 0.0056 | ||||
AGPAT2 | U56418 | Moderate detection | 8/8 | 0.028 | ER enzyme converting LPA to PA |
AGPAT3 | NM_020132 | Strong detection | 8/8 | 0.002 | ER enzyme converting LPA to PA |
AGPAT4 | NM_020133.1 | Not detected | 0/8 | 0.25 | Converts LPA to PA |
LYPLA1 | AF077198.1 | Strong detection | 8/8 | 0.0002 | Hydrolyzes lysophosphatidylcholine to LPA |
LYPLA2 | NM_007260.1 | Strong detection | 8/8 | 0.014 | Hydrolyzes lysophosphatidylcholine to LPA |
EDG2 | 45580697 | Moderate detection | 4/8 | 0.068 | LPA receptor |
EDG3 | NM_005226 | Not detected | 0/8 | 0.43 | LPA receptor |
EDG4 | NM_004720.3 | Not detected | 0/8 | 0.63 | LPA receptor |
EDG7 | NM_012152.1 | Not detected | 0/8 | 0.33 | LPA receptor |
EDG8 | AF317676 | Not detected | 0/8 | 0.97 | S-1-P receptor |
P2Y9 | NM_005296.1 | Not detected | 0/8 | 0.63 | LPA receptor, platelet |
ROCK2 | D87931 | Strong detection | 7/8 | 0.010 | LPA activated kinase |