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Table 1 Characteristics of studies investigating LDL-cholesterol lowering effect of plant stanols consumption in doses of 4 g or more

From: Dose-dependent LDL-cholesterol lowering effect by plant stanol ester consumption: clinical evidence

Reference Subject characteristics Treatment characteristics
  N Age (years) Men (%) weight status Baseline bloodcholesterol Study design Vehicle Dose of plant stanols (g/d)1 Duration (wk)
[10]Nguyen 1999 83 49 30   mildly hypercholesterolaemic open label, dose-response in comparison to respective baselines margarine, soya yoghurt 3 / 6 / 10 2
[11]Plat & Mensink 2000 112 33 37 normal normocholesterolaemic parallel, randomized, double-blind, placebo-controlled margarine, shortening for baking 0 / 3.82 / 43 8
[12]Cater et al. 2005 8 58 75 slightly overweight mildly hypercholesterolaemic cross-over,randomized, double-blind, placebo-controlled margarine 0 / 2 / 3 / 4 6
[13]Gylling et al. 2010 49 62 35 slightly overweight mildly hypercholesterolaemic parallel, randomized, double-blind, placebo-controlled margarine, oat based drink 0 / 8.8 10
[14]Mensink et al. 2010 93 56 53 slightly overweight mildly hypercholesterolaemic parallel, randomized, double-blind, placebo-controlled margarine, soya based yoghurt 0 / 3 / 6 / 9 4
  1. 1 in each study group, 2vegetable oil based plant stanols, 3 pine wood based plant stanol.