The role of Odontella aurita, a marine diatom rich in EPA, as a dietary supplement in dyslipidemia, platelet function and oxidative stress in high-fat fed rats

Table 5 Plasma total lipid fatty acid composition of rats after 7 weeks of treatment

Diet groups	C	COA	HF	HFOA	p value
Fatty acids (% molar)
14:0	0.32 ± 0.07^ab	0.34 ± 0.10^a	0.20 ± 0.03^b	0.23 ± 0.06^b	0.025
16:0	17.84 ± 1.86^a	16.94 ± 1.65^ab	15.11 ± 0.72^bc	14.83 ± 1.46^c	0.010
16:1	1.51 ± 0.27^a	1.69 ± 0.28^a	0.56 ± 0.05^b	0.58 ± 0.12^b	< 0.001
18:0	9.41 ± 0.74^b	8.76 ± 0.60^b	12.08 ± 0.85^a	11.29 ± 0.69^a	< 0.001
18:1n-7 + n-9	18.60 ± 3.84	16.84 ± 2.85	15.87 ± 1.53	16.09 ± 2.39	N.S
18:2n-6	10.40 ± 0.87	10.99 ± 1.40	12.09 ± 0.96	10.98 ± 1.00	N.S
18:3n-3	0.18 ± 0.05	0.25 ± 0.04	0.24 ± 0.05	0.22 ± 0.04	N.S
20:1n-9	0.27 ± 0.06^a	0.34 ± 0.09^a	0.15 ± 0.03^b	0.16 ± 0.04^b	< 0.001
20:4n-6	23.25 ± 3.22	23.44 ± 2.96	26.64 ± 1.76	23.40 ± 3.48	N.S
20:5n-3	0.27 ± 0.07^b	0.60 ± 0.16^a	0.19 ± 0.05^b	0.33 ± 0.09^b	< 0.001
22:5n-3	0.48 ± 0.0.22	0.46 ± 0.06	0.33 ± 0.04	0.43 ± 0.07	N.S
22:6n-3	4.42 ± 1.19^ab	5.31 ± 0.66^a	3.64 ± 0.70^b	4.92 ± 0.70^a	0.042
SFA	27.58 ± 1.49	26.10 ± 1.83	27.40 ± 0.86	26.35 ± 1.77	N.S
MUFA	20.38 ± 4.14	18.87 ± 2.89	16.57 ± 1.60	16.83 ± 2.51	N.S
Total n-3	5.22 ± 1.1^ab	5.99 ± 1.04^a	4.22 ± 0.68^b	5.71 ± 0.67^a	0.024
Total n-6	33.64 ± 2.54^b	34.44 ± 2.62^b	38.74 ± 0.95^a	34.39 ± 3.88^b	0.035
MUFA / SFA	0.73 ± 0.11	0.72 ± 0.10	0.60 ± 0.07	0.64 ± 0.07	N.S
n-6 / n-3	6.63 ± 1.18^b	5.88 ± 1.09^b	9.35 ± 1.37^a	6.12 ± 1.19^b	< 0.001

Results are expressed as mean ± SD (n=5). After a one-way ANOVA, Student–Newman–Keuls (SNK) multiple comparison test, results are arranged in increasing order from left to right: a > b > c (p < 0.05). C, control; COA, control + O. aurita; HF, high fat; HFOA, high fat + O. aurita. N.S: Not significant.

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