The role of Odontella aurita, a marine diatom rich in EPA, as a dietary supplement in dyslipidemia, platelet function and oxidative stress in high-fat fed rats

Table 7 Platelet phospholipids fatty acid composition of rats after 7 weeks of treatment

Diet groups	C	HF	HFOA	p value
Fatty acids (% molar)
14:0	0.44 ± 0.04	0.53 ± 0.10	0.59 ± 0.06	N.S
16:0	24.54 ± 0.55	24.93 ± 0.28	25.72 ± 0.68	N.S
16:1	0.50 ± 0.05^a	0.26 ± 0.02^b	0.25 ± 0.00^b	< 0.001
18:0	13.90 ± 0.29	14.49 ± 0.12	14.25 ± 0.99	N.S
18:1n-7 + n-9	8.82 ± 0.20^a	7.71 ± 0.28^b	7.06 ± 0.33^c	< 0.001
18:2n-6	4.33 ± 0.04	4.66 ± 0.39	4.39 ± 0.10	N.S
18:3n-3	0.49 ± 0.02	0.57 ± 0.03	0.54 ± 0.05	N.S
20:1n-9	0.46 ± 0.01	0,57 ± 0.06	0.54 ± 0.06	N.S
20:4n-6	25.88 ± 0.33^a	23.80 ± 0.52^b	23.80 ± 0.65^b	0.004
20:5n-3	0.20 ± 0.03	0.17 ± 0.03	0.22 ± 0.00	N.S
22:5n-3	0.36 ± 0.06^b	0.39 ± 0.05^b	0.52 ± 0.03^a	0.018
22:6n-3	0.47 ± 0.08	0.48 ± 0.05	0.63 ± 0.14	N.S
SFA	38.89 ± 0.45^b	39.95 ± 0.22^a	40.57 ± 0.38^a	0.004
MUFA	9.78 ± 0.21^a	8.55 ± 0.25^b	7.85 ± 0.28^c	< 0.001
Total n-3	1.52 ± 0.19^b	1.63 ± 0.05^b	1.92 ± 0.12^a	0.029
Total n-6	30.21 ± 0.36^a	28.47 ± 0.54^b	28.19 ± 0.71^b	0.009
MUFA / SFA	0.25 ± 0.00^a	0.21 ± 0.00^b	0.19 ± 0.00^c	< 0.001
n-6 / n-3	20.02 ± 2.75^a	17.48 ± 0.86^b	14.71 ± 0.71^bc	0.025

Results are expressed as mean ± SD (n=6). After a one-way ANOVA, Student–Newman–Keuls (SNK) multiple comparison test, results are arranged in increasing order from left to right: a > b > c (p < 0.05). C, control; HF, high fat; HFOA, high fat + O. aurita. N.S: Not significant.

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