Table 3 Association of lipid associated SNPs with hypertension and diabetes related traits based on minor allele and within sib pair association estimates from the Fulker model
From: Evaluation of seven common lipid associated loci in a large Indian sib pair study
Gene | SNP | Hypertension | Systolic blood pressure | Diastolic blood pressure | Fasting glucose | Fasting insulin | BMI |
|---|---|---|---|---|---|---|---|
APOA5 | rs662799 | 0.84(0.65, 1.08), 0.18 | −0.02(−0.09, 0.04), 0.51 | −0.002(−0.07, 0.06), 0.12 | −0.014(−0.08, 0.05), 0.67 | 0.04(−0.02, 0.11), 0.20 | 0.014(−0.05, 0.08), 0.63 |
APOB | rs562338 | 0.79(0.58, 1.06), 0.12 | −0.05(−0.13, 0.02), 0.17 | −0.03(−0.11, -0.05), 0.45 | −0.02(−0.10, 0.05), 0.53 | 0.01(−0.07, 0.09), 0.74 | 0.02(−0.05, 0.10), 0.49 |
CETP | rs1864163 | 1.02(0.79, 1.31), 0.85 | −0.03(−0.09, 0.03), 0.36 | −0.03(−0.10, 0.03), 0.35 | 0.02(−0.04, 0.09), 0.49 | 0.009(−0.06, 0.08), 0.81 | 0.03(−0.03, 0.09), 0.40 |
GCKR | rs780094 | 1.26(1.00, 1.59), 0.05 | 0.02(−0.04, 0.08), 0.46 | 0.04(−0.02, 0.10), 0.22 | −0.01(−0.08, 0.05), 0.63 | 0.06( −0.003, 0.13), 0.06 | −0.004(−0.06, 0.05), 0.88 |
LDLR | rs6511720 | 1.88(1.23, 2.88), 0.003 | 0.06(−0.05, 0.17), 0.28 | −0.01(−0.12, 0.10), 0.82 | 0.02(−0.09, 0.13), 0.73 | −0.08(−0.19, 0.04), 0.19 | −0.01(−0.11, 0.09), 0.84 |
LIPC | rs4775041 | 0.98(0.78, 1.22), 0.83 | −0.004(−0.07, 0.06), 0.9 | −0.01(−0.08, 0.05), 0.65 | −0.009(−0.07, 0.05), 0.79 | 0.03(−0.04, 0.09), 0.43 | −0.02(−0.08, 0.03), 0.42 |
LPL | rs10503669 | 0.74(0.54, 1.02), 0.07 | −0.09(−0.17, -0.005), 0.04 | −0.04(−0.13, 0.04), 0.35 | −0.10(−0.18, -0.01), 0.02 | −0.11(−0.19, -0.02), 0.02 | −0.04(−0.12, 0.03), 0.28 |