Table 5 Within sib pair association statistics for seven SNPs with lead lipid traits after stratifying for Sex
From: Evaluation of seven common lipid associated loci in a large Indian sib pair study
Gene | Trait tested | Males | Females | Interaction effect |
|---|---|---|---|---|
APOA5 | Triglycerides | 0.19 (0.09, 0.29, p=0.0002) | 0.17 (0.07, 0.27, p=0.001) | 0.10 (−0.04, 0.25, p=0.16) |
APOB | LDL-Cholesterol | −0.01 (−0.13, 0.10, p=0.79) | −0.19 (−0.32, -0.06, p=0.005) | −0.17 (−0.35, 0.01), p=0.07 |
CETP | HDL-Cholesterol | −0.02 (−0.11, 0.07, p=0.63) | 0.01 (−0.09, 0.12, p=0.79) | 0.03 (−0.11, 0.18, p=0.66) |
GCKR | Triglycerides | 0.09 (−0.006, 0.18, p=0.07) | 0.13 (0.03, 0.23, p=0.009) | 0.06 (−0.09, 0.21, p=0.42) |
LDLR | LDL-Cholesterol | −0.18 (−0.33, -0.02, p=0.02) | 0.10 (−0.09, 0.28, p=0.30) | 0.27 (0.01, 0.52, p=0.04) |
LIPC | HDL-Cholesterol | 0.04 (−0.04, 0.12, p=0.36) | 0.13 (0.02, 0.23, p=0.01) | 0.09 (−0.05, 0.23, p=0.21) |
LPL | Triglycerides | −0.14 (−0.27, -0.01, p=0.03) | −0.21 (−0.34, -0.08, p=0.001) | −0.06 (−0.26, 0.13, p=0.54) |