Table 6 Within sib pair association statistics for seven SNPs with lead lipid traits after stratifying for location
From: Evaluation of seven common lipid associated loci in a large Indian sib pair study
Gene | Trait tested | Urban | Rural | Interaction effect |
|---|---|---|---|---|
APOA5 | Triglycerides | 0.18 (0.09, 0.27, p=0.0001) | 0.19 (0.06, 0.32, p=0.004) | −0.009 (−0.18, 0.16, p=0.91) |
APOB | LDL-Cholesterol | −0.04 (−0.20, 0.12, p=0.63) | −0.11 (−0.22, -0.005, p=0.34 | −0.06 (−0.26, 0.13, p=0.53) |
CETP | HDL-Cholesterol | −0.02 (−0.16, 0.22, p=0.78) | −0.005 (−0.09, 0.08, p=0.90) | 0.04 (−0.13, 0.21, p=0.64) |
GCKR | Triglycerides | 0.11 (0.03, 0.20, p=0.009) | 0.14 (0.01, 0.26, p=0.03) | −0.004 (−0.16, 0.15, p=0.96) |
LDLR | LDL-Cholesterol | −0.05 (−0.20, 0.09, p=0.47) | −0.13 (−0.36, 0.10, p=0.26) | 0.04 (−0.13, 0.21, p=0.64) |
LIPC | HDL-Cholesterol | 0.05 (−0.04, 0.13, p=0.29) | 0.17 (0.04, 0.29, p=0.007) | −0.11 (−0.27, 0.05, p=0.18) |
LPL | Triglycerides | −0.21 (−0.32, -0.09, p=0.001) | −0.14 (−0.30, 0.02, p=0.09) | −0.07 (−0.28, 0.14, p=0.50) |