Table 2 Genotype distribution and allele frequencies of these three polymorphisms (ABCA1R219K, LIPC-250 G/A and CETP Taq1B) in cases and controls
Genotypes and alleles | AD patients (n/%) | Controls (n/%) | χ2 | P |
|---|---|---|---|---|
ABCA1R219K | ||||
RR | 47(45.2) | 31(29.8) | 3.282 | 0.070 |
RK | 51(49.0) | 56(53.8) | 0.234 | 0.629 |
KK | 6(5.8) | 17(16.3) | 5.261 | 0.022 |
χ2 = 8.777 P = 0.012 | ||||
R/K(%) | 70/30 | 57/43 | 3.646 | 0.056 |
LIPC-250 G/A | ||||
GG | 29(27.9) | 14(13.5) | 5.233 | 0.022 |
GA | 64(61.5) | 82(78.8) | 2.219 | 0.136 |
AA | 11(10.6) | 8(7.7) | 0.474 | 0.491 |
χ2 = 7.925 P = 0.019 | ||||
G/A(%) | 59/41 | 53/47 | 0.731 | 0.393 |
CETP Taq1B | ||||
B1B1 | 14(13.5) | 9(8.7) | 1.087 | 0.297 |
B1B2 | 61(58.7) | 80(76.9) | 2.560 | 0.110 |
B2B2 | 29(27.9) | 15(14.4) | 4.455 | 0.035 |
χ2 = 8.102 P = 0.017 | ||||
B1/B2(%) | 57/43 | 53/47 | 0.323 | 0.570 |