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Table 2 Genotype distribution and allele frequencies of these three polymorphisms (ABCA1R219K, LIPC-250 G/A and CETP Taq1B) in cases and controls

From: Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer’s disease

Genotypes and alleles AD patients (n/%) Controls (n/%) χ2 P
ABCA1R219K     
 RR 47(45.2) 31(29.8) 3.282 0.070
 RK 51(49.0) 56(53.8) 0.234 0.629
 KK 6(5.8) 17(16.3) 5.261 0.022
  χ2 = 8.777 P = 0.012   
 R/K(%) 70/30 57/43 3.646 0.056
LIPC-250 G/A     
 GG 29(27.9) 14(13.5) 5.233 0.022
 GA 64(61.5) 82(78.8) 2.219 0.136
 AA 11(10.6) 8(7.7) 0.474 0.491
  χ2 = 7.925 P = 0.019   
 G/A(%) 59/41 53/47 0.731 0.393
CETP Taq1B     
 B1B1 14(13.5) 9(8.7) 1.087 0.297
 B1B2 61(58.7) 80(76.9) 2.560 0.110
 B2B2 29(27.9) 15(14.4) 4.455 0.035
  χ2 = 8.102 P = 0.017   
 B1/B2(%) 57/43 53/47 0.323 0.570