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Figure 5 | Lipids in Health and Disease

Figure 5

From: Inhibitory effect of the combination therapy of simvastatin and pinocembrin on atherosclerosis in apoE-deficient mice

Figure 5

The combination of simvastatin and pinocembrin decreased atherosclerotic lesions on the aorta in the apoE−/− mice. A: the gross appearance of the ascending aorta to the abdominal aorta. B: lipid accumulation staining using oil red O of longitudinally opened aorta in the apoE−/− mice. C: aortic root plaque stained by oil red O in ApoE−/− Mice. D: the ratio of the plaque area stained by oil red O to the total luminal surface area. E: the aortic root plaque area. Data are presented as the mean ± SEM (n = 8). *P < 0.05, **P < 0.01 versus vehicle-treated group; #P < 0.05, ##P < 0.01 versus simvastatin treatment.

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