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Figure 4 | Lipids in Health and Disease

Figure 4

From: Dihydrotestosterone regulating apolipoprotein M expression mediates via protein kinase C in HepG2 cells

Figure 4

Effect of DHT on plasma ApoM of DHT-treated C57BL/6 J mice. C57BL/6 J female mice were ovariectomized at the age of 3 months and treated at the age of 7 months. Animals were randomized into four groups (n = 6), with two groups receiving vehicle (propylene glycol) alone, and two groups receiving 3 mg/kg DHT. All animals were treated daily by sc injections for 7d or 14d, fasted overnight, and killed using CO2. Levels of plasma ApoM were determined by Western blotting as described in “Materials and methods.” Data are expressed relative to the vehicle-treated group (100%). Data are represented as means ± S.D. (n = 6 for each treated group). Lane 1, vehicle-treated mice for 7d, Lane 2, DHT-treated mice for 7d, Lane 3, vehicle-treated mice for 14d and Lane 4, DHT-treated mice for 14d. Significant differences were determined using ANOVA. *P < 0.05 vs. vehicle-treated mice, ***, P < 0.01 vs. vehicle-treated mice.

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