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Figure 5 | Lipids in Health and Disease

Figure 5

From: E series prostaglandins alter the proliferative, apoptotic and migratory properties of T98G human glioma cells in vitro

Figure 5

Effect of IBP on T98G cell migration. (A) Migration of T98G in the presence or absence of 25 μM or 50 μM IBP in the monolayer scratch assay. Number of migrating cells per unit area. Statistical significance, * p < 0.05 vs control, n = 8 in control, n = 16 in 25 μM and n = 16 in 50 μM. (B) Representative images of Hoechst 33342-labelled control and 50 μM IBP treated cells. Start point at time zero indicated by line1 and average maximum migratory distance possible in a 10 h period indicated by line 2. (C) Migration of T98G in the presence or absence of 25 μM or 50 μM IBP in the transwell assay. Number of migrating cells per x100 field. Statistical significance, * p < 0.0005 vs control, n = 12. (D) Representative images of crystal violet stained control and 50 μM IBP treated cells.

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