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Figure 2 | Lipids in Health and Disease

Figure 2

From: Fatty acids do not pay the toll: effect of SFA and PUFA on human adipose tissue and mature adipocytes inflammation

Figure 2

Proinflammatory effects of SFA and PUFA on human adipose tissue and adipocytes. A and B: IL-6 secretion in the medium of adipose tissue (A) and adipocytes (B) culture after treatment with PUFA and SFA for 12 hours with LPS (1 μg/ml) as positive control. Results were expressed in arbitrary units normalised to control (1 represents from 15 to 20 ng/ml IL6, depending on the patient). The graph shows the mean ± SD of the results from 4 patients (n=6 for each condition, for each patient). C and D: TNF-alpha secretion in the medium of adipose tissue (C) and adipocytes (D) after treatment with PUFA and SFA for 6 hours, with LPS (1 μg/ml) as positive control. Results were expressed in arbitrary units, normalised to control (1 represents from 0.02 to 0.05 ng/ml TNF-alpha, depending on the patient). The graph shows the mean ± SD of the results from 4 patients (n=6 for each condition, for each patient). E and F: MCP-1 secretion in the medium of adipose tissue (E) and adipocytes (F) after treatment with PUFA and SFA for 12 hours, with LPS (1 μg/ml) as positive control. Results were expressed in arbitrary units, normalised to control (1 represents from 10 to 15 ng/ml MCP-1, depending on the patient). The graph shows the mean ± SD of the results from 3 patients (n=6 for each condition, for each patient).

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