Figure 1From: Multiple roles of dihomo-γ-linolenic acid against proliferation diseasesProducts of dihomo-γ-linolenic acid. In mammal tissues and cells, DGLA is converted to AA by an alternating sequence of Δ5 desaturation. DGLA can be converted to PG1 via the cyclooxygenase pathway and/or converted to 15-HETrE via the 15-lipoxygenase pathway. During the process of conversion mediated by different oxygenases, free radicals and lipid perioxidation and various metabolites were generated.Back to article page