Table 4 Comparison of clinical characteristics and serum lipid levels among the genotypes stratified by gender in overall population

Male/n

166

224

47

-

-

Age (years)

70.15 ± 21.11

68.85 ± 21.37

69.62 ± 23.38

0.177

0.838

Body mass index (kg/m²)

21.48 ± 3.35

21.58 ± 3.43

21.17 ± 4.04

0.285

0.752

Systolic blood pressure (mmHg)

146.767 ± 26.80

142.51 ± 27.92

144.98 ± 26.29

1.169

0.312

Diastolic blood pressure (mmHg)

88.76 ± 12.64

85.90 ± 11.89

88.04 ± 14.55

2.615

0.074

Total cholesterol (mmol/L)

4.937 ± 1.09

4.88 ± 1.00

5.36 ± 1.12

4.237

0.015

Triglyceride (mmol/L)

1.08(0.67)

0.95(0.78)

1.18(0.74)

7.329

0.026

HDL-C (mmol/L)

1.47 ± 0.30

1.57 ± 0.33

1.71 ± 0.36

10.803

0.000

LDL-C (mmol/L)

2.85 ± 0.96

2.74 ± 0.94

2.86 ± 0.93

0.788

0.455

HDL-C/LDL-C

0.66 ± 0.89

0.67 ± 0.34

0.68 ± 0.33

0.010

0.990

Female/n

227

286

71

-

-

Age (years)

73.93 ± 21.91

78.76 ± 19.30

79.56 ± 18.62

4.249

0.015

Body mass index (kg/m²)

21.24 ± 4.52

20.47 ± 3.30

21.59 ± 3.70

3.777

0.023

Systolic blood pressure (mmHg)

150.42 ± 29.39

154.15 ± 33.03

154.17 ± 32.08

0.972

0.379

Diastolic blood pressure (mmHg)

88.18 ± 12.45

86.59 ± 13.09

88.35 ± 12.78

1.188

0.305

Total cholesterol (mmol/L)

4.99 ± 0.92

5.12 ± 0.96

4.88 ± 0.93

2.392

0.092

Triglyceride (mmol/L)

1.07(0.80)

1.00(0.49)

1.00(0.60)

2.739

0.254

HDL-C (mmol/L)

1.50 ± 0.30

1.59 ± 0.35

1.62 ± 0.29

5.739

0.003

LDL-C (mmol/L)

2.87 ± 0.85

3.02 ± 0.86

2.74 ± 0.84

3.810

0.023

HDL-C/LDL-C

0.57 ± 0.23

0.58 ± 0.29

0.66 ± 0.29

2.954

0.053