Table 3 Enzymatic activity of the lipid metabolism after administration of PLs (adapted from Gundermann 1993 [58])
Enzyme | Activity after PL administration | Consequence |
|---|---|---|
Lipoprotein lipase (LPL) | ⇑ | Acceleration of the breakdown of lipoproteins rich in TG, which results in a reduction of LDL and VLDL |
Hepatic triglyceride lipase (HTGL) | ⇑ | |
Acyl-cholesterol acyltransferase (ACAT) | ⇓ | Reduction of cholesterol ester deposition in cells |
Cholesterol esterase | ⇑ | Hydrolysis of cholesterol esters in the cells. Free cholesterol can be transferred to the blood and incorporated into HDL by LCAT, which results in higher HDL-level |
Lecithin cholesterol acyl transferase (LCAT) | ⇑ |