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Figure 3 | Lipids in Health and Disease

Figure 3

From: Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells

Figure 3

Effects of oleic acid on palmitic acid-induced decreases in IR and GLUT4 expression and 2DG uptake activity. Differentiated L6 myotubes were treated with 750 μM palmitic acid without or with the indicated concentrations of oleic acid for 14 h. (A) IR and GLUT4 expression determined by western blotting. (B) Dose-dependent effects of oleic acid on 2DG uptake activity in the presence of 750 μM palmitic acid in the absence or presence of 100 nM insulin. Different letters indicate significant changes (p < 0.05).

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