Table 5 Effect of rutin (RT) and/or ascorbic acid (AA) on kidney nucleic acids and total protein levels in high-cholesterol diet (HCD) fed rats following 6 weeks of supplementation

Control

101.35 ± 18.33

110.56 ± 17.93

266.30 ± 26.60

240.16 ± 19.00

12.21 ± 0.47

11.26 ± 0.63

RT (0.2%)

108.33 ± 24.25

117.22 ± 12.08

271.22 ± 27.50

254.10 ± 11.80

12.15 ± 0.49

11.63 ± 0.43

AA (0.4%)

110.25 ± 18.05

114.21 ± 21.35

278.77 ± 17.28

248.52 ± 13.58

11.84 ± 0.53

11.95 ± 0.24

RT (0.1%) + AA (0.2%)

114.35 ± 17.37

112.60 ± 21.77

269.24 ± 31.53

250.20 ± 13.05

12.20 ± 0.60

11.53 ± 0.56

HCD (1% cholesterol + 0.5% cholic acid)

76.07 ± 15.99

75.64 ± 16.37 ^a

247.01 ± 13.17

186.95 ± 19.04 ^a

11.45 ± 0.35

10.64 ± 0.35

RT (0.2%) + HCD

81.45 ± 10.83 ^b

79.63 ± 12.47 ^ab

252.52 ± 20.72

192.11 ± 13.22 ^ab

11.54 ± 0.28

10.80 ± 0.31 ^b

AA (0.4%) + HCD

79.62 ± 11.54 ^c

84.46 ± 9.00 ^ac

255.66 ± 18.87

193.82 ± 20.91 ^ac

11.76 ± 0.37

10.96 ± 0.15 ^c

RT (0.1%) + AA (0.2%) + HCD

86.64 ± 11.89 ^d

102.49 ± 14.25 ^e

258.09 ± 21.65

219.12 ± 15.86 ^ade

11.87 ± 0.31

11.15 ± 0.24