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Table 7 Effect of rutin (RT) and/or ascorbic acid (AA) on kidney Total Cholesterol and Triglycerides levels in high-cholesterol diet (HCD) fed rats following 6 weeks of supplementation

From: Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats

Treatment (in rat chow) Total Cholesterol (mg/g wet tissue) Triglycerides (mg/g wet tissue)
  Male Female Male Female
Control 13.58 ± 1.72 16.75 ± 1.39 6.14 ± 0.94 6.42 ± 0.82
RT (0.2%) 12.99 ± 1.36 16.64 ± 1.24 6.29 ± 1.02 6.35 ± 1.10
AA (0.4%) 12.36 ± 1.12 16.42 ± 1.44 6.11 ± 0.80 6.18 ± 0.70
RT (0.1%) + AA (0.2%) 12.33 ± 0.46 16.72 ± 1.10 5.83 ± 0.54 6.00 ± 0.77
HCD (1% cholesterol + 0.5% cholic acid) 24.86 ± 2.80 a 32.66 ± 4.53 a 10.11 ± 1.11 a 13.46 ± 1.19 a
RT (0.2%) + HCD 21.87 ± 2.02 abe 27.69 ± 2.18 abe 9.40 ± 1.04 ab 10.95 ± 1.96 abe
AA (0.4%) + HCD 19.43 ± 0.83 ace 23.28 ± 2.51 ace 7.90 ± 0.59 ace 8.45 ± 0.69 ace
RT (0.1%) + AA (0.2%) + HCD 16.99 ± 1.41 ade 20.59 ± 2.89 ade 6.19 ± 0.83 e 7.38 ± 0.78 e
  1. Data were expressed as Mean ± S.D and analyzed using one-way ANOVA followed by Student Newman-Keuls method as post hoc test. Six rats were used in each group. aAll treated groups vs. Control; bRT + HCD vs RT group; cAA + HCD vs AA group; dRT + AA + HCD vs RT + AA group; eRT + HCD, AA + HCD and RT + AA + HCD vs HCD