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Table 7 Effect of rutin (RT) and/or ascorbic acid (AA) on kidney Total Cholesterol and Triglycerides levels in high-cholesterol diet (HCD) fed rats following 6 weeks of supplementation

From: Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats

Treatment

(in rat chow)

Total Cholesterol (mg/g wet tissue)

Triglycerides (mg/g wet tissue)

 

Male

Female

Male

Female

Control

13.58 ± 1.72

16.75 ± 1.39

6.14 ± 0.94

6.42 ± 0.82

RT (0.2%)

12.99 ± 1.36

16.64 ± 1.24

6.29 ± 1.02

6.35 ± 1.10

AA (0.4%)

12.36 ± 1.12

16.42 ± 1.44

6.11 ± 0.80

6.18 ± 0.70

RT (0.1%) + AA (0.2%)

12.33 ± 0.46

16.72 ± 1.10

5.83 ± 0.54

6.00 ± 0.77

HCD (1% cholesterol + 0.5% cholic acid)

24.86 ± 2.80 a

32.66 ± 4.53 a

10.11 ± 1.11 a

13.46 ± 1.19 a

RT (0.2%) + HCD

21.87 ± 2.02 abe

27.69 ± 2.18 abe

9.40 ± 1.04 ab

10.95 ± 1.96 abe

AA (0.4%) + HCD

19.43 ± 0.83 ace

23.28 ± 2.51 ace

7.90 ± 0.59 ace

8.45 ± 0.69 ace

RT (0.1%) + AA (0.2%) + HCD

16.99 ± 1.41 ade

20.59 ± 2.89 ade

6.19 ± 0.83 e

7.38 ± 0.78 e

  1. Data were expressed as Mean ± S.D and analyzed using one-way ANOVA followed by Student Newman-Keuls method as post hoc test. Six rats were used in each group. aAll treated groups vs. Control; bRT + HCD vs RT group; cAA + HCD vs AA group; dRT + AA + HCD vs RT + AA group; eRT + HCD, AA + HCD and RT + AA + HCD vs HCD