Association of ATP binding cassette transporter G8 rs4148217 SNP and serum lipid levels in Mulao and Han nationalities

Li, Qing; Wei, Xian-Liang; Yin, Rui-Xing

doi:10.1186/1476-511X-11-46

Table 5 Relationship between serum lipid parameters and environmental risk factors in Mulao and Han nationalities

From: Association of ATP binding cassette transporter G8 rs4148217 SNP and serum lipid levels in Mulao and Han nationalities

Lipid	Risk factor	Unstandardized coefficient	Std. error	Standardized coefficient	t	P
Han plus Mulao
TC	Age	0.011	0.002	0.147	5.475	0.000
	Alcohol consumption	0.212	0.043	0.132	4.976	0.000
	Diastolic blood pressure	0.012	0.003	0.116	4.194	0.001
	Waist circumference	0.011	0.002	0.147	5.475	0.000
TG	Waist circumference	0.052	0.007	0.209	7.773	0.000
	Diastolic blood pressure	0.019	0.005	0.101	3.793	0.000
	Blood glucose	0.115	0.033	0.091	3.528	0.000
	Alcohol consumption	0.442	0.076	0.145	5,561	0.006
HDL-C	Waist circumference	−0.007	0.002	−0.141	−3.844	0.000
	Alcohol consumption	0.106	0.019	0.173	5.732	0.000
	Body mass index	−0.022	0.005	−0.116	−4.497	0.000
	Age	0.002	0.001	0.055	2.065	0.039
	Gender	0.107	0.028	0.123	3.825	0.000
LDL-C	Age	0.010	0.001	0.183	6.952	0.000
	Body mass index	0.047	0.007	0.181	6.860	0.000
ApoA1	Age	0.001	0.001	0.062	2.327	0.020
	Gender	0.073	0.020	0.113	3.825	0.000
	Body mass index	−0.009	0.003	−0.093	−3.473	0.001
	Alcohol consumption	0.126	0.014	0.276	8.515	0.000
	Ethnic group	−0.047	0.017	0.073	−2.327	0.020
ApoB	Waist circumference	0.009	0.001	0.179	6.787	0.000
	Ethnic group	−0.123	0.022	−0.145	5.258	0.000
	Blood glucose	0.020	0.007	0.074	2.816	0.005
	Systolic blood pressure	0.002	0.001	0.088	3.279	0.001
	Gender	0.072	0.023	0.084	3.099	0.002
ApoA1/ApoB	Waist circumference	−0.011	0.004	−0.117	−3.129	0.002
	Gender	0.209	0.052	0.130	4.008	0.000
	Alcohol consumption	0.102	0.036	0.090	2.832	0.005
	Body mass index	−0.023	0.009	−0.097	−2.649	0.008
	Age	−0.004	0.001	−0.084	−3.182	0.001
Han
TC	Waist circumference	0.016	0.005	0.113	3.065	0.002
	Age	0.009	0.003	0.119	3.176	0.002
	Alcohol consumption	0.269	0.056	0.172	4.808	0.000
	Diastolic blood pressure	0.019	0.004	0.187	5.002	0.000
	Blood glucose	0.055	0.024	0.083	2.290	0.022
TG	Wrist circumference	0.084	0.014	0.275	5.850	0.000
	Blood glucose	0.246	0.052	0.169	4.689	0.000
	Diastolic blood pressure	0.036	0.008	0.162	4.380	0.000
	Age	−0.014	0.006	−0.087	−2.341	0.020
	Body mass index	0.087	0.033	0.123	−2.657	0.008
	Alcohol consumption	0.559	0.122	0.162	4.574	0.000
HDL-C	Waist circumference	−0.012	0.003	−0.224	−4.699	0.000
	Gender	0.167	0.039	0.201	4.272	0.000
	Alcohol consumption	0.114	0.025	0.192	4.552	0.000
	Body mass index	−0.012	0.006	−0.102	−2.184	0.029
	Cigarette smoking	0.085	0.035	0.101	2.406	0.016
LDL-C	Age	0.012	0.002	0.207	5.722	0.000
	Body mass index	0.048	0.009	0.194	5.373	0.000
ApoA1	Alcohol consumption	0.133	0.015	0.372	8.975	0.000
	Body mass index	−0.014	0.003	−0.195	−5.539	0.000
	Gender	0.103	0.023	0.206	4.522	0.000
	Cigarette smoking	0.082	0.021	0.160	3.885	0.000
ApoB	Waist circumference	0.005	0.001	0.191	4.177	0.000
	Gender	−0.040	0.016	−0.098	−2.417	0.016
	Ages	0.001	0.001	0.097	2.548	0.011
	Systolic blood pressure	0.003	0.001	0.193	3.915	0.000
	Blood glucose	0.020	0.004	0.167	4.859	0.000
	Alcohol consumption	0.032	0.011	0.111	2.822	0.005
	Body mass index	0.008	0.003	0.135	3.032	0.003
ApoA1/ApoB	Waist circumference	−0.010	0.003	−0.161	−3.554	0.000
	Body mass index	−0.030	0.006	−0.210	−4.650	0.000
	Age	−0.003	0.001	−0.1101	−2.957	0.003
	Alcohol consumption	0.111	0.029	0.157	3.856	0.000
	Cigarette smoking	0.167	0.041	0.165	4.097	0.000
	Gender	0.253	0.046	0.248	5.400	0.000
Mulao
TC	Age	0.012	0.003	0.161	4.170	0.000
	Alcohol consumption	0.171	0.065	0.102	2.621	0.009
	Waist circumference	−0.020	0.005	−0.161	4.170	0.000
TG	Waist circumference	0.045	0.007	0.252	6.567	0.000
	Alcohol consumption	0.278	0.083	0.128	3.342	0.001
HDL-C	Alcohol consumption	0.088	0.029	0.139	3.021	0.003
	Gender	0.093	0.042	0.102	2.218	0.027
	Body mass i ndex	0.040	0.005	−0.280	−7.339	0.000
LDL-C	Age	0.008	0.002	0.147	4.042	0.000
	Body mass index	0.049	0.010	0.177	4.599	0.000
ApoA1	Alcohol consumption	0.112	0.026	0.206	4.350	0.000
	Gender	0.082	0.037	0.105	2.221	0.027
ApoB	Waist circumference	0.011	0.003	0.168	4.190	0.000
	Gender	−0.113	0.046	−0.097	−2.439	0.015
ApoA1/ApoB	Age	−0.006	0.003	−0.086	−2.179	0.028
	Waist circumference	−0.018	0.005	0.152	−3.872	0.000
	Cigarette smoking	−0.159	0.078	−0.080	−2.031	0.043

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; ApoA1/ApoB, the ratio of apolipoprotein A1 to apolipoprotein B.

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