Association of ATP binding cassette transporter G8 rs4148217 SNP and serum lipid levels in Mulao and Han nationalities

Li, Qing; Wei, Xian-Liang; Yin, Rui-Xing

doi:10.1186/1476-511X-11-46

Lipids in Health and Disease

Table 6 Relationship between serum lipid parameters and and environmental risk factors in males and females in both ethnic groups

From: Association of ATP binding cassette transporter G8 rs4148217 SNP and serum lipid levels in Mulao and Han nationalities

Lipid	Risk factor	Unstandardized coefficient	Std. error	Standardized coefficient	t	P
Han/male
TC	Diastolic blood pressure	0.033	0.005	0.322	6.013	0.000
	Alcohol consumption	0.289	0.073	0.209	3.980	0.000
	Blood glucose	0.083	0.036	0.122	2.320	0.021
TG	Waist circumference	0.080	0.023	0.189	3.473	0.000
	Cigarette smoking	1,240	0.286	0.231	4.376	0.000
	Blood glucose	0.439	0.107	0.228	4.108	0.000
	Age	−0.024	0.012	−0.118	−2.082	0.038
HDL-C	Waist circumference	−0.014	0.003	−0.252	−4.650	0.000
	Alcohol consumption	0.107	0.027	0.210	3.883	0.000
LDL-C	Cigarette smoking	−0.329	0.074	−0.238	−4.436	0.000
	Body mass index	0.039	0.012	0.172	3.216	0.001
ApoA1	Alcohol consumption	0.133	0.018	0.393	7.565	0.000
	Body mass index	−0.013	0.004	−0.166	−3.269	0.001
	Cigarette smoking	0.067	0.024	0.144	2.756	0.006
ApoB	Body mass index	0.006	0.003	0.118	1.980	0.049
	Blood glucose	0.022	0.006	0.187	3.736	0.000
	Alcohol consumption	0.035	0.012	0.143	2.851	0.005
	Diastolic blood pressure	0.004	0.001	0.238	4.644	0.000
	Waist circumference	0.005	0.002	0.176	2.942	0.004
ApoA1/ApoB	Body mass index	−0.029	0.008	−0.230	−3.742	0.000
	Cigarette smoking	0.104	0.041	0.136	2.554	0.011
	Alcohol consumption	0.104	0.029	0.187	3.528	0.000
	Waist circumference	−0.011	0.004	0.183	−2.996	0.003
Han/female
TC	Age	0.022	0.003	0.315	7.271	0.000
	Waist circumference	0.023	0.006	0.161	3.720	0.000
TG	Waist circumference	0.040	0.006	0.277	6.317	0.000
	Diastolic blood pressure	0.011	0.004	0.110	2.512	0.012
	Blood glucose	0.128	0.029	0.187	4.369	0.000
HDL-C	Waist circumference	−0.008	0.004	−0.102	−2.227	0.026
LDL-C	Age	0.020	0.003	0.336	7.585	0.000
	Waist circumference	0.021	0.005	0.175	4.031	0.000
	Cigarette smoking	−0.527	0.244	−0.095	−2.163	0.031
ApoA1	Cigarette smoking	0.155	0.072	0.099	2.152	0.032
	Waist circumference	0.023	0.006	0.161	3.720	0.000
ApoB	Blood glucose	0.019	0.006	0.151	3.466	0.001
	Age	0.003	0.001	0.195	4.287	0.000
	Cigarette smoking	−0.118	0.053	−0.097	−2.238	0.026
	Waist circumference	0.007	0.001	0.273	6.379	0.000
ApoA1/ApoB	Body mass index	−0.038	0.007	−0.223	−5.127	0.000
	Cigarette smoking	0.590	0.143	0.183	4.114	0.000
	Age	−0.007	0.002	−0.219	−4.903	0.000
Mulao/male
TC	Body mass index	0.064	0.021	0.173	3.117	0.002
	Alcohol consumption	0.169	0.071	0.133	2.385	0.018
TG	Waist circumference	0.062	0.012	0.276	5.053	0.000
HDL-C	Alcohol consumption	0.106	0.029	0.194	3.602	0.000
	Body mass index	−0.045	0.009	−0.284	−5.276	0.000
LDL-C	Body mass index	0.041	0.014	0.163	2.901	0.004
ApoA1	Alcohol consumption	0.118	0.025	0.258	4.697	0.000
ApoB	Waist circumference	0.011	0.004	0.156	2.785	0.006
ApoA1/ApoB	Alcohol consumption	0.116	0.042	0.150	2.736	0.007
	Waist circumference	−0.018	0.004	−0.230	−4.184	0.000
Mulao/female
TC	Age	0.014	0.004	0.181	3.726	0.000
	Body mass index	0.046	0.019	0.120	2.465	0.014
TG	Body mass index	0.062	0.013	0.233	4.822	0.000
HDL-C	Body mass index	−0.035	0.007	−0.251	−5.219	0.000
LDL-C	Body mass index	0.053	0.014	0.183	3.845	0.000
	Age	0.013	0.003	0.218	4.577	0.000
ApoA1	Waist circumference	−0.018	0.004	−0.230	−4.184	0.000
	Body mass index	0.046	0.019	0.120	2.465	0.014
	Cigarette smoking	−0.118	0.055	−0.100	−3.238	0.006
ApoB	Blood glucose	0.046	0.017	0.128	2.638	0.009
	Wrist circumference	0.013	0.003	0.205	4.228	0.000
ApoA1/ApoB	Waist circumference	−0.016	0.008	−0.128	−2.807	0.018
	Age	−0.011	0.004	−0.140	−2.849	0.005

TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; ApoA1/ApoB, the ratio of apolipoprotein A1 to apolipoprotein B.

Back to article page

ISSN: 1476-511X

Contact us

General enquiries: journalsubmissions@springernature.com