Skip to main content

Table 3 Plasma concentration of total free aminothiols (glutathione, homocysteine, cysteine and cysteinylglycine) at baseline and after the 28-day treatment with fenofibrate or placebo

From: Treatment of chronic hemodialysis patients with low-dose fenofibrate effectively reduces plasma lipids and affects plasma redox status

Parameter Healthy controls* Baseline After Placebo After Fenofibrate
Glutathione [nmol/mL] 5.3 ± 1.2 3.3 ± 0.9 3.4 ± 1.1 4.2 ± 1.4#$
Homocysteine [nmol/mL] 2.6 ± 1.7 6.6 ± 3.9 7.8 ± 5.0 9.0 ± 7.4##
Cysteine [nmol/mL] 47 ± 22 160 ± 48 163 ± 47 167 ± 51
Cysteinylglycine [nmol/ml] 7 ± 2 24 ± 4.5 23 ± 4 25 ± 7
  1. * healthy controls – historic cohort from Bald E et al. [19]
  2. # p = 0.01 vs baseline; $ p = 0.02 vs placebo
  3. ## p = 0.04 vs baseline