From: Association of rs5888 SNP in the scavenger receptor class B type 1 gene and serum lipid levels
Genotype | n | TC (mmol/L) | TG (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | ApoAI (g/L) | ApoB (g/L) | ApoAI/ApoB |
---|---|---|---|---|---|---|---|---|
Bai Ku Yao | ||||||||
CC | 359 | 4.30 ± 0.94 | 0.98 (0.69) | 1.66 ± 0.42a | 2.54 ± 0.76 | 1.31 ± 0.32a | 0.84 ± 0.23 | 1.68 ± 0.76 |
CT | 219 | 4.44 ± 0.89 | 1.02 (0.62) | 1.69 ± 0.41a | 2.64 ± 0.75 | 1.33 ± 0.33a | 0.87 ± 0.22 | 1.67 ± 0.72 |
TT | 20 | 4.04 ± 0.96 | 1.10 (0.52) | 1.43 ± 0.36 | 2.42 ± 0.88 | 1.14 ± 0.27 | 0.78 ± 0.27 | 1.66 ± 1.00 |
F | – | 2.770 | 0.388 | 4.001 | 1.625 | 3.878 | 1.871 | 0.023 |
P | – | 0.063 | 0.824 | 0.019 | 0.198 | 0.021 | 0.155 | 0.977 |
Male | ||||||||
CC | 176 | 4.39 ± 1.09 | 1.18 (0.95) | 1.70 ± 0.49a | 2.54 ± 0.92 | 1.38 ± 0.37a | 0.83 ± 0.23 | 1.82 ± 0.95 |
CT | 99 | 4.43 ± 1.01 | 1.05 (0.69) | 1.74 ± 0.46b | 2.55 ± 0.86 | 1.39 ± 0.40a | 0.83 ± 0.23 | 1.86 ± 0.92 |
TT | 11 | 3.97 ± 1.07 | 1.25 (0.61) | 1.30 ± 0.45 | 2.35 ± 0.99 | 1.10 ± 0.35 | 0.76 ± 0.30 | 1.74 ± 1.32 |
F | – | 0.985 | 1.822 | 4.743 | 0.253 | 3.769 | 0.559 | 0.117 |
P | – | 0.375 | 0.402 | 0.009 | 0.776 | 0.024 | 0.572 | 0.889 |
CC | 176 | 4.39 ± 10.9 | 1.18 (0.95) | 1.70 ± 0.49 | 2.54 ± 0.92 | 1.38 ± 0.37 | 0.83 ± 0.23 | 1.82 ± 0.95 |
CT + TT | 110 | 4.38 ± 1.02 | 1.06(0.65) | 1.70 ± 0.47 | 2.53 ± 0.87 | 1.36 ± 0.40 | 0.82 ± 0.24 | 1.85 ± 0.96 |
F | – | 0.003 | −1.246 | 0.024 | 0.014 | 0.222 | 0.106 | 0.072 |
P | – | 0.959 | 0.213 | 0.877 | 0.907 | 0.638 | 0.745 | 0.788 |
Female | ||||||||
CC | 183 | 4.22 ± 0.76 | 0.90 (0.51) | 1.63 ± 0.33 | 2.53 ± 0.58 | 1.24 ± 0.25 | 0.84 ± 0.22 | 1.56 ± 0.48 |
CT | 120 | 4.45 ± 0.78c | 1.00 (0.61) | 1.65 ± 0.35 | 2.72 ± 0.64c | 1.27 ± 0.25 | 0.90 ± 0.19 | 1.49 ± 0.44 |
TT | 9 | 4.19 ± 0.84 | 1.05 (0.38) | 1.51 ± 0.24 | 2.57 ± 0.74 | 1.16 ± 0.16 | 0.84 ± 0.24 | 1.46 ± 0.31 |
F | – | 3.562 | 2.102 | 0.655 | 3.881 | 1.198 | 2.601 | 1.121 |
P | – | 0.030 | 0.350 | 0.520` | 0.022 | 0.303 | 0.076 | 0.327 |
CC | 183 | 4.22 ± 0.76 | 0.90 (0.51) | 1.63 ± 0.33 | 2.53 ± 0.58 | 1.24 ± 0.25 | 0.84 ± 0.22 | 1.56 ± 0.48 |
CT + TT | 129 | 4.43 ± 0.78 | 1.01(0.60) | 1.64 ± 0.34 | 2.71 ± 0.65 | 1.26 ± 0.24 | 0.89 ± 0.20 | 1.48 ± 0.44 |
F | – | 6.103 | −1.429 | 0.054 | 7.234 | 0.542 | 4.473 | 2.224 |
P | – | 0.014 | 0.153 | 0.817 | 0.008 | 0.462 | 0.035 | 0.137 |
Han Chinese | ||||||||
CC | 317 | 4.73 ± 0.96 | 0.97 (0.82) | 1.76 ± 0.49a | 2.75 ± 0.76 | 1.36 ± 0.31a | 0.82 ± 0.19 | 1.74 ± 0.54 |
CT | 228 | 4.71 ± 1.01 | 1.05 (0.78) | 1.72 ± 0.44a | 2.73 ± 0.85 | 1.35 ± 0.31a | 0.82 ± 0.21 | 1.74 ± 0.54 |
TT | 40 | 4.54 ± 1.05 | 0.99 (0.97) | 1.55 ± 0.35 | 2.58 ± 0.67 | 1.23 ± 0.21 | 0.81 ± 0.18 | 1.56 ± 0.35 |
F | – | 0.821 | 1.764 | 4.125 | 0.965 | 3.824 | 0.044 | 2.313 |
P | – | 0.441 | 0.414 | 0.017 | 0.381 | 0.022 | 0.957 | 0.100 |
Male | ||||||||
CC | 145 | 4.73 ± 0.94 | 1.11 (0.89) | 1.68 ± 0.54 | 2.74 ± 0.72 | 1.34 ± 0.36 | 0.83 ± 0.18 | 1.67 ± 0.50 |
CT | 114 | 4.70 ± 1.07 | 1.13 (0.90) | 1.64 ± 0.39 | 2.74 ± 0.91 | 1.32 ± 0.32 | 0.84 ± 0.23 | 1.67 ± 0.54 |
TT | 18 | 4.59 ± 1.22 | 1.23 (1.79) | 1.43 ± 0.26 | 2.47 ± 0.65 | 1.18 ± 0.18 | 0.83 ± 0.20 | 1.49 ± 0.37 |
F | – | 0.233 | 1.500 | 2.793 | 1.070 | 2.474 | 0.036 | 1.160 |
P | – | 0.793 | 0.472 | 0.063 | 0.344 | 0.086 | 0.965 | 0.315 |
CC | 145 | 4.73 ± 0.94 | 1.11 (0.89) | 1.68 ± 0.54 | 2.74 ± 0.72 | 1.34 ± 0.36 | 0.83 ± 0.18 | 1.67 ± 0.50 |
CT + TT | 132 | 4.69 ± 1.09 | 1.15(0.94) | 1.61 ± 0.38 | 2.71 ± 0.88 | 1.30 ± 0.30 | 0.84 ± 0.22 | 1.65 ± 0.52 |
F | – | 0.212 | −1.071 | 1.746 | 0.139 | 1.216 | 0.041 | 0.124 |
P | – | 0.646 | 0.284 | 0.187 | 0.709 | 0.271 | 0.839 | 0.725 |
Female | ||||||||
CC | 172 | 4.74 ± 0.98 | 0.91 (0.80) | 1.83 ± 0.43 | 2.76 ± 0.80 | 1.38 ± 0.27 | 0.81 ± 0.19 | 1.80 ± 0.57 |
CT | 114 | 4.69 ± 0.94 | 0.96 (0.60) | 1.78 ± 0.48 | 2.70 ± 0.78 | 1.37 ± 0.31 | 0.80 ± 0.19 | 1.80 ± 0.53 |
TT | 22 | 4.54 ± 0.91 | 0.94 (0.69) | 1.68 ± 0.38 | 2.68 ± 0.69 | 1.29 ± 0.23 | 0.80 ± 0.15 | 1.64 ± 0.34 |
F | – | 0.559 | 0.914 | 1.343 | 0.373 | 1.139 | 0.115 | 0.937 |
P | – | 0.572 | 0.633 | 0.263 | 0.689 | 0.322 | 0.891 | 0.393 |
CC | 172 | 4.74 ± 0.98 | 0.91 (0.80) | 1.83 ± 0.43 | 2.76 ± 0.80 | 1.38 ± 0.27 | 0.81 ± 0.19 | 1.80 ± 0.57 |
CT + TT | 136 | 4.66 ± 0.93 | 0.96(0.60) | 1.76 ± 0.46 | 2.69 ± 0.77 | 1.36 ± 0.30 | 0.80 ± 0.18 | 1.77 ± 0.50 |
F |  | 0.644 | −0.657 | 1.841 | 0.730 | 0.602 | 0.227 | 0.255 |
P | Â | 0.423 | 0.511 | 0.176 | 0.394 | 0.439 | 0.634 | 0.614 |