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Table 1 Characteristics of study subjects

From: Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease

Characteristic Control (n = 100) All Hyperlipidemia (n = 255) P value Hyperlipidemia without CAD (n = 100) Hyperlipidemia with CAD (n = 155) P value
Age (years) 63.0 ± 10.7 65.2 ± 10.7 0.162 65.2 ± 10.2 65.3 ± 11.0 0.850
Male, n (%) 35 (70.0 %) 162 (63.5 %) 0.382 57 (57.0 %) 105 (67.7 %) 0.082
BMI (kg/m2) 23.7 ± 2.3 24.3 ± 2.8 0.125 23.8 ± 2.6 24.6 ± 2.8 0.024
Smoking, n (%) 22 (44.0 %) 116 (45.5 %) 0.847 34 (34.0 %) 82 (52.9 %) 0.003
Hypertension, n (%) 28 (56 %) 159 (62.4 %) 0.399 60 (60.0 %) 99 (63.9 %) 0.533
Diabetes, n (%) 9 (18 %) 58 (22.7 %) 0.459 22 (22.0 %) 36 (23.2 %) 0.820
Statin therapy, n (%) - 110 (43.1 %) - 43 (43.0 %) 67 (43.2 %) 0.972
TC (mmol/L) 4.01 ± 0.73 4.56 ± 0.99 <0.001 4.34 ± 0.91 4.70 ± 1.01 0.013
TG (mmol/L) 1.09 ± 0.32 1.90 ± 0.90 <0.001 1.78 ± 0.94 1.97 ± 0.87 0.025
LDL-C (mmol/L) 2.48 ± 0.60 2.81 ± 0.70 0.012 2.68 ± 0.69 2.89 ± 0.69 0.035
HDL-C (mmol/L) 1.13 ± 0.18 1.08 ± 0.22 0.035 1.11 ± 0.21 1.05 ± 0.22 0.020
Fasting glucose (mmol/L) 4.95 ± 0.93 5.08 ± 1.41 0.477 5.08 ± 1.45 5.07 ± 1.39 0.878
Number of disease vessels       
Single-vessel, n (%) - - - - 52 (33.6 %) -
Double-vessel, n (%) - - - - 40 (25.8 %) -
Triple-vessel, n (%) - - - - 63 (40.6 %) -
  1. CAD = coronary artery disease; BMI = body mass index; TC = total cholesterol; TG = triglyceride; LDL-C = low density lipoprotein cholesterol; HDL-C = high density lipoprotein cholesterol.