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Table 1 Characteristics of study subjects

From: Plasma levels of lipometabolism-related miR-122 and miR-370 are increased in patients with hyperlipidemia and associated with coronary artery disease

Characteristic

Control (n = 100)

All Hyperlipidemia (n = 255)

P value

Hyperlipidemia without CAD (n = 100)

Hyperlipidemia with CAD (n = 155)

P value

Age (years)

63.0 ± 10.7

65.2 ± 10.7

0.162

65.2 ± 10.2

65.3 ± 11.0

0.850

Male, n (%)

35 (70.0 %)

162 (63.5 %)

0.382

57 (57.0 %)

105 (67.7 %)

0.082

BMI (kg/m2)

23.7 ± 2.3

24.3 ± 2.8

0.125

23.8 ± 2.6

24.6 ± 2.8

0.024

Smoking, n (%)

22 (44.0 %)

116 (45.5 %)

0.847

34 (34.0 %)

82 (52.9 %)

0.003

Hypertension, n (%)

28 (56 %)

159 (62.4 %)

0.399

60 (60.0 %)

99 (63.9 %)

0.533

Diabetes, n (%)

9 (18 %)

58 (22.7 %)

0.459

22 (22.0 %)

36 (23.2 %)

0.820

Statin therapy, n (%)

-

110 (43.1 %)

-

43 (43.0 %)

67 (43.2 %)

0.972

TC (mmol/L)

4.01 ± 0.73

4.56 ± 0.99

<0.001

4.34 ± 0.91

4.70 ± 1.01

0.013

TG (mmol/L)

1.09 ± 0.32

1.90 ± 0.90

<0.001

1.78 ± 0.94

1.97 ± 0.87

0.025

LDL-C (mmol/L)

2.48 ± 0.60

2.81 ± 0.70

0.012

2.68 ± 0.69

2.89 ± 0.69

0.035

HDL-C (mmol/L)

1.13 ± 0.18

1.08 ± 0.22

0.035

1.11 ± 0.21

1.05 ± 0.22

0.020

Fasting glucose (mmol/L)

4.95 ± 0.93

5.08 ± 1.41

0.477

5.08 ± 1.45

5.07 ± 1.39

0.878

Number of disease vessels

      

Single-vessel, n (%)

-

-

-

-

52 (33.6 %)

-

Double-vessel, n (%)

-

-

-

-

40 (25.8 %)

-

Triple-vessel, n (%)

-

-

-

-

63 (40.6 %)

-

  1. CAD = coronary artery disease; BMI = body mass index; TC = total cholesterol; TG = triglyceride; LDL-C = low density lipoprotein cholesterol; HDL-C = high density lipoprotein cholesterol.