Lipids in Health and Disease

Table 2 Effect of fenugreek on the body weight, energy intake, tissue weights and plasma parameters of experiment 1

From: Fenugreek with reduced bitterness prevents diet-induced metabolic disorders in rats

	Ctrl			Fen			FRB⁶
	Ctrl			Fen			1.2%			2.4%			4.8%
Total energy intake (kJ)	32,156	±	225^a	32,233	±	175^a	32,017	±	177^a	28,789	±	377^b	26,268	±	1,240^b
Final body weight (g)	754	±	22^a	748	±	16^a	714	±	9^a	625	±	16^b	546	±	19^c
EER¹ (mg/kJ)	3.95	±	0.37^a	4.05	±	0.46^a	2.75	±	0.14^a	0.80	±	0.23^b	−2.98	±	0.58^c
Liver weight (g)	24.2	±	0.9^a	23.2	±	1.3^a	21.5	±	0.8^ab	18.9	±	0.5^bc	16.6	±	0.5^c
EWAT² weight (g)	23.7	±	1.3^a	23.8	±	1.1^a	21.4	±	1.2^a	12.8	±	1.2^b	7.9	±	1.0^c
Soleuse weight (g)	0.19	±	0.01^ab	0.21	±	0.01^a	0.15	±	0.02^bc	0.13	±	0.01^c	0.11	±	0.01^c
Plasma TG³ (mmol/L)	2.67	±	0.53	3.05	±	0.57	4.03	±	0.64	3.46	±	0.61	2.93	±	0.52
Plasma TC⁴ (mmol/L)	2.00	±	0.18	1.84	±	0.15	1.58	±	0.09	1.45	±	0.05*	1.29	±	0.07*
AST (U/L)	65.3	±	5.4	53.1	±	2.6	52.3	±	2.6*	53.3	±	1.4*	56.0	±	3.2
ALT (U/L)	22.5	±	3.3	18.9	±	1.3	29.6	±	2.2*	40.1	±	1.7*	51.8	±	3.7*
AST/ALT⁵	1.13	±	0.09^a	1.05	±	0.09^a	0.65	±	0.02^bc	0.49	±	0.02^c	0.04	±	0.03^c

Ctrl: Control group, Fen: Fenugreek group. ¹EER (mg/kJ) = Body weight gain (mg)/Total food intake (kJ). ²EWAT: Epididymal white adipose tissue. ³TG: Triglyceride. ⁴TC: Total cholesterol. ⁵The relative values for Normal rats' data; AST/ALT = AST (U/L)/ALT (U/L)/Normal rats' data. ⁶FRB contains 82% of protodioscin converted to dioscin. Values are expressed as Mean ± SEM for 8 rats. Mean without a common superscript letter is significantly different, P < 0.05 (ANOVA). Asterisks indicate a difference from Ctrl: P < 0.05 (T-test).

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