Table 2 Effect of Viola odorata (Vo.Cr) on serum lipids, glucose, diet consumption and body weight in rats fed on atherogenic diet.
From: Studies on the antihypertensive and antidyslipidemic activities of Viola odorata leaves extract
Parameters | Normal diet (n = 7) | Atherogenic diet (n = 8) | Atherogenic + Atorvastatin 10 mg/kg (n = 6) | Atherogenic + Vo.Cr 300 mg/kg (n = 7) | Atherogenic + Vo.Cr 600 mg/kg (n = 8) |
|---|---|---|---|---|---|
Total cholesterol (mg/100 ml) | 76.29 ± 5.67 | 295 ± 27.37$$$ | 129.7 ± 9.70*** | 211.7 ± 12.83* | 140.3 ± 14.58*** |
HDL-C (mg/100 ml) | 29.94 ± 2.70 | 18.10 ± 0.89$$$ | 27.06 ± 1.83* | 15.35 ± 1.96 | 26.07 ± 1.71* |
LDL-C (mg/100 ml) | 31.91 ± 5.71 | 259.5 ± 27.4$$$ | 87.41 ± 8.88*** | 180.5 ± 12.43* | 99.50 ± 14.25*** |
Triglycerides (mg/100 ml) | 72.25 ± 4.41 | 86.36 ± 3.69 | 76.31 ± 5.82 | 78.99 ± 4.17 | 73.71 ± 2.16 |
Atherogenic index | 1.68 ± 0.31 | 15.71 ± 2.01$$$ | 2.19 ± 0.76*** | 13.92 ± 1.65 | 4.49 ± 0.55*** |
Glucose (mg/100 ml) | 107.4 ± 5.74 | 86.77 ± 6.42 | 113.8 ± 3.68 | 109.7 ± 5.68 | 106.8 ± 5.67 |
Diet consumption g/day/kg | 129.4 ± 6.28 | 115.9 ± 3.74 | 101.2 ± 4.35 | 100.3 ± 3.15 | 97.58 ± 2.56* |
% change in body weight | 29.13 ± 2.19 | 44.05 ± 1.90$$$ | 34.74 ± 2.09* | 34.97 ± 1.54* | 33.49 ± 1.60** |