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Table 2 Effect of Viola odorata (Vo.Cr) on serum lipids, glucose, diet consumption and body weight in rats fed on atherogenic diet.

From: Studies on the antihypertensive and antidyslipidemic activities of Viola odorata leaves extract

Parameters Normal diet
(n = 7)
Atherogenic diet
(n = 8)
Atherogenic +
Atorvastatin
10 mg/kg
(n = 6)
Atherogenic + Vo.Cr
300 mg/kg
(n = 7)
Atherogenic
+ Vo.Cr
600 mg/kg
(n = 8)
Total cholesterol
(mg/100 ml)
76.29 ± 5.67 295 ± 27.37$$$ 129.7 ± 9.70*** 211.7 ± 12.83* 140.3 ± 14.58***
HDL-C (mg/100 ml) 29.94 ± 2.70 18.10 ± 0.89$$$ 27.06 ± 1.83* 15.35 ± 1.96 26.07 ± 1.71*
LDL-C (mg/100 ml) 31.91 ± 5.71 259.5 ± 27.4$$$ 87.41 ± 8.88*** 180.5 ± 12.43* 99.50 ± 14.25***
Triglycerides
(mg/100 ml)
72.25 ± 4.41 86.36 ± 3.69 76.31 ± 5.82 78.99 ± 4.17 73.71 ± 2.16
Atherogenic index 1.68 ± 0.31 15.71 ± 2.01$$$ 2.19 ± 0.76*** 13.92 ± 1.65 4.49 ± 0.55***
Glucose (mg/100 ml) 107.4 ± 5.74 86.77 ± 6.42 113.8 ± 3.68 109.7 ± 5.68 106.8 ± 5.67
Diet consumption g/day/kg 129.4 ± 6.28 115.9 ± 3.74 101.2 ± 4.35 100.3 ± 3.15 97.58 ± 2.56*
% change in body weight 29.13 ± 2.19 44.05 ± 1.90$$$ 34.74 ± 2.09* 34.97 ± 1.54* 33.49 ± 1.60**
  1. Abbreviations: ANOVA: analysis of variance; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol.
  2. Values shown are mean ± SEM, n = 6-8
  3. $$$ P < 0.001 compared with normal controls
  4. * P < 0.05; ** P < 0.01; *** P < 0.001 compared with atherogenic controls.
  5. (One way ANOVA followed by Tukey's post-test)