Table 2 Distribution of R219K, R1587K and I883M polymorphisms and allele frequencies according to sex

R219K

RR

39 (17.3%)

186 (82.7%)

0.08*

RK

45 (23.8%)

144 (76.2%)

KK

3(9.4%)

29 (90.6%)

R1587K

RR

37 (17.5%)

174 (82.5%)

0.12*

RK

45 (23.5%)

146 (76.5%)

KK

5 (11.4%)

39 (88.6%)

I883M

II

64 (20.7%)

245 (79.3%)

0.66*

IM

22 (17.2%)

106 (82.8%)

MM

1 (12.5%)

7 (87.5 %)

Allele frequencies for R219K polymorphism

R allele frequency

0.71

0.72

0.85**

K allele frequency

0.29

0.28

Allele frequencies for R1587K polymorphism

R allele frequency

0.68

0.69

0.85**

K allele frequency

0.32

0.31

Allele frequencies for I883M polymorphism

I allele frequency

0.86

0.83

0.4**

M allele frequency

0.17

0.14